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ADVANCES IN ANTIVIRAL DRUG DESIGN, VOLUME 4
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To order this title, and for more information, click here
Edited By
E. De Clercq, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium
Reviews
"All six chapters in the current volume are up-to-date, interesting reading, and written by experts on each subject...The first chapter
on "New Anti-HIV Agents in Preclinical or Clinical Development" is written by the editor, who is a recognized authority in this area.
It is an excellent overview of current advances in the clinic and laboratory. Not only does this review thoroughly cover drugs acting
by conventional mechamisms, such as reverse transcriptase and protease inhibition, it also details agents operating by novel mechanisms...A
highlight of the volume is the chapter by Gilead co-workes Jin and Kim entitled "Design of Neuraminidase Inhibitors as Anti-Influenza
Virus Agents". This is an excellent description of the medical chemistry of an important new class of antiviral drugs based on enzyme
X-ray structures and structure-activity relationships...it provides very useful information and it is thorough in some areas...it should
be an essential acquisition for complete libraries in academic institutions and pharmaceutical companies."
--Thomas W. Bell, University
of Nevada, Reno for JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 126, 2004
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