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THE HUMAN GENOME
The Human Genome
A User's Guide
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Second Edition

By
Julia Richards, University of Michigan, Ann Arbor, MI
R. Scott Hawley, Stowers Institute for Medical Research, Kansas City, MO

Description
This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is becoming a commonplace scientific discussion on the evening news. Join authors Julia Richards and Scott Hawley as they examine the biological foundations of humanity, looking at the science behind the sensation and the current and potential impact of the study of the genome on our society. The Human Genome, Second Edition is ideal for students and non-professionals, but will also serve as a fitting guide for the novice geneticist by providing a scientific, humanistic, and ethical frame of reference for a more detailed study of genetics.

Contents
Acknowledgments Preface

SECTION 1: The Basics of Heredity
1. Slaying Molecular Dragons: Brenda's Tale 2. The Answer in a Nutshell: Genes, Proteins, and the Basis of Life 3. Mendel and the Concept of the Gene 4. Human Mendelian Genetics 5. One Man's Trait Is Another Man's Disease

SECTION 2: The Central Dogma of Molecular Biology
6. DNA: The Genetic Alphabet 7. The Central Dogma of Molecular Biology: How Genes Encode Proteins 8. Splicing the Modular Gene 9. Orchestrating the Human Genome

SECTION 3: How Chromosomes Move
10. So What are Chromosomes Anyway? 11. How Cells Move Your Genes Around 12. Passing Genes Between Generations 13. The Chromosomal Basis of Heredity

SECTION 4: Mutation
14. Absent Essentials and Monkey Wrenches 15. How We Detect Mutations 16. We Are All Mutants 17. What Constitutes Normal? 18. Mutations in Mammoth Genes 19. Expanded Repeat Traits

SECTION 5: Genes, Chromosomes, and Sex
20. The X and Y Chromosomes: The Odd Couple 21. Genetics of Sex, Gender, and Orientation 22. Aneuploidy: When Too Much or Too Little Counts

SECTION 6: Breaking the Rules
23. Imprinting 24. Imitating Heredity: One Trait, Many Causes

SECTION 7: The Human Genome Landscape
25. The Human Genome Project 26. There's Cloning and Then There's Cloning 27. The Human Genome Sequence 28. Finding Genes in the Human Genome

SECTION 8: Complex and Heterogeneous Traits
29. Genotype Phenotype Correlations 30. How Complex Can It Get? 31. Quantitative Traits 32. The MAOA Gene: Is There a Genetic Basis for Criminality? 33. The Multiple-Hit Hypothesis: The Genetics of Cancer

SECTION 9: Genetic Testing and Therapy
34. Genetic Testing and Screening 35. Magic Bullets: The Potential for Gene Therapy

SECTION 10: Fears, Faith, and Fantasies
36. Heroes Among Us 37. Fears, Faith, and Fantasies Credits Index

Bibliographic details
Paperback, 480 pages, publication date: OCT-2004
ISBN-13: 978-0-12-333462-6
ISBN-10: 0-12-333462-4
Imprint: ACADEMIC PRESS

Price and Ordering
Price:
EUR 52.95
USD 64.95
GBP 45
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Last update: 30 Nov 2009
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