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| THE CHEMOKINE FACTSBOOK
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Ligands and Receptors
To order this title, and for more information, click here
By
Krishna Vaddi, Postcript, Inc., Cambridge, Massachusetts, U.S.A.
Margaret Keller, Children's Hospital of Philadelphia, Pennsylvania, U.S.A.
Robert Newton, The DuPont Merck Pharmaceutical Co, Wilmington, Delaware, U.S.A.
Description
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties,
amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive
fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information
overload. Each volume provides a catalog of the essential properties of families of molecules. Gene organization, amino acid sequences,
physicochemical properties, and biological activity are presented using a common, easy-to-follow format. Taken together they compile
everything you want to know about proteins but are too busy to look for. The Chemokine FactsBook contains more than
40 entries on chemokines, and chemokine receptors from human or other origin, including IL-8, MCP-1, C5-a, RANTES, Lymphotactin, and
CC CKR-1.
The text provides information on tissue sources, target cells, physicochemical properties, transcription factors, regulation
of expression in disease, receptor-binding characteristics, gene structure and location, amino acid sequences, and accession numbers
and references.
Audience
Ideal for immunologists, cell biologists, biochemists, molecular biologists, pharmacologists, cancer biologists, developmental biologists,
biotechnologists, members of the pharmaceutical industry, and to medical researchers. Potential for bulk sales to pharmaceutical companies.
Contents
Introductory Chapters:
Introduction.
Organization of the Data.
Chemokines, An Overview.
Chemokine Families.
CXC Chemokines.
CC Chemokines.
Structural Features of Chemokines.
Chemokines as Angiogenic and Angiostatic Agents.
Chemokines as HIV Suppressive Factors.
Chemokine Receptors, An Overview.
Chemokines:
CXC or I Family Chemokines: IL-8, MGSA, PF4, NAP-2, IP-10, MIP-2, ENA-78,
EMF-1, GCP-2, SDF-1, CC or J Family Chemokines: MCP-1, MCP-2, MCP-3, MIP-1a, MIP-1b, RANTES, I-309, C10, HCC-1, C or K Family Chemokines:
Lymphotactin, SCM-1.
Chemokine Receptors:
XC or I Chemokine Receptors: IL-8 Receptor A, IL-8 Receptor B. CC or J Chemokine
Receptors: CC CKR-1, CC CKR-2, CC CKR-3, CC CKR-4. Chemoattractant Receptors: C5a Receptor, FPR. Chemoattractant Receptors: PAF Receptor,
DARC.
Viral Chemokine Receptors: US28, RCRF3.
Orphan Chemokine Receptors: CMK-BRL-1, BLR-1/MDR15, HUMSTR, V28, EBI1.
Subject Index.
| Bibliographic details |
Paperback, 205 pages, publication date: APR-1997
ISBN-13: 978-0-12-709905-7
ISBN-10: 0-12-709905-0
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
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Last update: 3 Oct 2009
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