By
Thomas Steckler, Johnson & Johnson Pharmaceutical, Beerse, Belgium
N.H. Kalin, University of Wisconsin Medical School, Department of Psychiatry and Health Emotions Research Institute, Madison, WI, U.S.A.
J.M.H.M. Reul, Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, U.K.
Description
The
Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous
system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception
of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively
reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together
the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical
and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry.
Part 1 addresses basic
aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems
and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality.
Part 2 treats
the complexity of short-term and long-term regulation of stress responsivity, the role of stress in psychiatric disorders as based on
both preclinical and clinical evidence, and the current status with regard to new therapeutic strategies targetting stress-related disorders.
Audience:
Researchers and clinicians in the fields of neuroscience, neurobiology, physiology, immunology, psychology, and psychiatry.
