 |
|
| EX VIVO CELL THERAPY
| |
| | |
|
|
To order this title, and for more information, click here
Edited By
Klaus Schindhelm, University of New South Wales and Graduate School of Biomedical Engineering, Sydney, Australia
Robert Nordon, University of New South Wales, Sydney, Australia
Description
Over the last two decades advances in the understanding of disease at a cellular and molecular level has led to innovative therapies that
are based on the administration of cells which have been modified outside of the body. Ex vivo cell therapy is in essence gene therapy
delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections such as
AIDS, or other conditions such as cancer or genetic diseases. These manipulations include the purification and culture of therapeutic
cell subtypes, as well as elimination of cells which cause disease (cancer cells or immune cells reacting to the body itself). Gene therapy
can be delivered by transfer of therapeutic genes to cells in culture, which are then given to the patient to treat fatal infections
such as AIDS, cancer or genetic diseases. For small-scale laboratory methods to become clinically applicable processes, these new therapies
require efficient technologies for cell separation, cell production in culture and gene transfer. This book integrates the recent advances
in biological and clinical research with developments in cell-based technologies to provide a comprehensive review for clinicians, researchers,
biotechnologists and biomedical engineers working in this rapidly developing area. The biotechnology and pharmaceutical industry requires
a broad perspective for development of future technologies, and this text will provide then with an excellent overview of this rapidly
evolving field.
Audience
Oncologists, Hematologists, Immunologists, Gene Therapists, and HIV Specialists
Contents
R.E. Nordon and K. Schindhelm, Introduction.L. Robb, A.G. Elefanty, and C.G. Begley, Transcriptional Control of Hematopoieses.
R. Starr and N.A. Nicola, Cell Signaling by Hemopoietic Growth Factor Receptors.P.J. Simmons, D.N. Haylock, and J.-P. Lévesque,
Influence of Cytokines and Adhesion Molecules on Hematopoietic Stem Cell Development.P.A. Rowlings, Allogeneic Hematopoietic
Stem Cell Transplantation.U. Hahn and L.B. To, Autologous Stem Cell Transplantation.M.R. Vowels, Cord Blood Stem
Cell Transplantation.S.R. Riddell, E.H. Warren, D. Lewinsohn, C. Yee, and P.D. Greenberg, Reconstitution of Immunity by Adoptive
Immunotherapy with T Cells.L.Q. Sun, M. Miller, and G. Symonds, Exogenous Gene Transfer into Lymphoid and Hematopoietic Progenitor
Cells.C. Dowding, T. Leemhuis, A. Jakubowski, and C. Reading, Process Development for Ex Vivo Cell Therapy.R.E.
Nordon and K. Schindhelm, Cell Separation.P.W. Zandstra, C.J.Eaves, and J.M. Piret, Environmental Requirements of Hematopoietic
Progenitor Cells in Ex Vivo Expansion Systems.R. Mandalam, M. Koller, and A. Smith, Ex Vivo Hematopoietic Cell Expansion
for Bone Marrow Transplantation.M. Raponi and G. Symonds, Gene Delivery Technology: Nonviral and Viral Vector Systems.R.E.
Nordon and K. Schindhelm, Summary and Future Directions.
Index.
| Bibliographic details |
Hardbound, 356 pages, publication date: MAY-1999
ISBN-13: 978-0-12-624960-6
ISBN-10: 0-12-624960-1
Imprint: ACADEMIC PRESS
|
| Price and Ordering |
Price:
GBP 84
EUR 98.95
USD 136
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
092/900
Last update: 4 Sep 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company