By
Dick Swaab, Netherlands Institute for Brain Research, University of Amsterdam, The Netherlands
Description
This volume in the
Handbook of Clinical Neurology (Series Editors: Michael J. Aminoff, Department of Neurology, University of
California, San Francisco, USA; François Boller, Bethesda, USA; Dick F. Swaab, Netherlands Institute for Neuroscience, Amsterdam, the
Netherlands)is the first major account of the human hypothalamus. Part II is system and disease oriented and deals with the clinic, and
with the neuropathology, neurobiology and genetics of vascular disorders, disorders of development and growth (including e.g. anencephaly,
septo-optic dysplasia and other midline defects), hypothalamic and pineal tumors, infections, neuroimmunological disorders such as neurosarcoidosis,
multiple sclerosis, and Langerhans-cell histiocytosis. After the neuropathology of the neurohypophysis has been dealt with, the background
of the different forms of diabetes insipidus and other drinking disorders, such as polydipsia and adipsia, inappropriate secretion of
vasopressin, and Wolfram syndrome are presented. Eating disorders such as, e.g. Prader-Willi syndrome, anorexia and bulimia nervosa,
are presented as typical hypothalamic diseases. Genetic disorders causing a defect in the migration of hypothalamic neurons are the
basis of Kallmann syndrome. Sexual differentiation of the brain is related to transsexuality and homo/heterosexuality.
Included in series
Handbook of Clinical Neurology
Handbook of Clinical Neurology
Audience:
Clinical neurologists and researchers in the neurosciences
