 |
|
| COMPREHENSIVE MEDICINAL CHEMISTRY II
| |
| | |
|
|
Volume 2: STRATEGY AND DRUG RESEARCH
To order this title, and for more information, click here
Edited By
Walter Moos, SRI International, Menlo Park, CA, USA and University of California-San Francisco, CA, USA
Description
Strategy and project management is very important in the pharmaceutical and biotechnology industries as it can take a decade and over
a billion dollars to develop a successful drug. This comprehensive volume presents academic, industry and other complementary viewpoints
on the drug research process with many illustrative examples, anecdotes and representative case studies. Experts evaluate the strengths
and weaknesses of old and new methods, the crossroads of tactics and strategy and market forces. Project management chapters highlight
decisions that must be made along the drug discovery pathway and investigate outsourcing, licensing, innovation and managing scientists.
The volume concludes with some case studies so that readers can examine practical applications of strategy and project management applied
to real life examples.
Audience
For students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.
Contents
Volume 2 Strategy and Drug Research
Introduction
2.01 The Intersection of Strategy and Drug Research
2.02
An Academic Perspective
2.03 An Industry Perspective
Organizational Aspects and Strategies for Drug Discovery and Development
2.04
Project Management
2.05 The Role of the Chemical Development, Quality, and Regulatory Affairs Teams in Turning a Potent Agent into
a Registered Product
2.06 Drug Development
2.07 In-House or Out-Source
2.08 Pharma versus Biotech: Contracts, Collaborations,
and Licensing
2.09 Managing Scientists, Leadership Strategies in Science
2.10 Innovation (Fighting against the Current)
2.11
Enabling Technologies in Drug Discovery: The Technical and Cultural Integration of the New with the Old
2.12 How and Why to Apply
the Latest Technology
2.13 How and When to Apply Absorption, Distribution, Metabolism, Excretion, and Toxicity
2.14 Peptide and
Protein Drugs: Issues and Solutions
2.15 Peptidomimetic and Nonpeptide Drug Discovery: Receptor, Protease, and Signal Transduction
Therapeutic Targets
2.16 Bioisosterism
2.17 Chiral Drug Discovery and Development – From Concept Stage to Market Launch
2.18
Promiscuous Ligands
Targets
2.19 Diversity versus Focus in Choosing Targets and Therapeutic Areas
2.20 G Protein-Coupled
Receptors
2.21 Ion Channels – Voltage Gated
2.22 Ion Channels – Ligand Gated
2.23 Phosphodiesterases
2.24 Protein Kinases
and Protein Phosphatases in Signal Transduction Pathways
2.25 Nuclear Hormone Receptors
2.26 Nucleic Acids (Deoxyribonucleic Acid
and Ribonucleic Acid)
2.27 Redox Enzymes
| Bibliographic details |
Hardbound, 1196 pages, publication date: NOV-2006
ISBN-13: 978-0-08-044515-1
ISBN-10: 0-08-044515-2
Imprint: ELSEVIER
|
| Price and Ordering |
Price:
GBP 285
USD 495
EUR 325
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
030/302
Last update: 3 Oct 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company