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| COMPREHENSIVE MEDICINAL CHEMISTRY II
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Volume 1: GLOBAL PERSPECTIVE
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Edited By
Peter Kennewell, Swindon, UK
Description
This volume provides and educative and authoriative discussions on the drug discovery and development process. It is divided into ten
sections and starts with personal recollections on the history and evolution of the drug discovery process. To illustrate the end result
of the drug discovery process, a large chapter reviews the major drug introductions over 1993-2003. Subsequent chapters examine the impact
of genomic technologies, new sources of drugs and alternatives to animal testing. The next section reviews the roles of enterprise and
pharamaceuticals companies, venture capitalists and academic-industrial relations in the drug discovery process. Social and ethical issues
are reviewed in the context of assessing health demands in developed, developing countries and also in relation to smaller scale diseases
(orphan drugs). Two chapters then review the bioethical and ethical issues facing the pharmaceutical industry. The volume concludes with
reviews on funding and regulartion and how intellectual property rights and patents are protected. With such a wide variety of topics
this volume will appeal to both scientists and non-scientists who need to understand how and why the pharmaceutical industry works.
Audience
For students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries
Contents
Volume 1 Global Perspective
Historical Perspective and Outlook
1.01 Reflections of a Medicinal Chemist: Formative Years through
Thirty-Seven Years Service in
the Pharmaceutical Industry
1.02 Drug Discovery: Historical Perspective, Current Status, and Outlook
1.03
Major Drug Introductions
The Impact of New Genomic Technologies
1.04 Epigenetics
1.05 Personalized Medicine
1.06 Gene Therapy
Sources
of New Drugs
1.07 Overview of Sources of New Drugs
1.08 Natural Product Sources of Drugs: Plants, Microbes, Marine Organisms, and
Animals
1.09 Traditional Medicines
1.10 Biological Macromolecules
1.11 Nutraceuticals
Animal Experimentation
1.12 Alternatives
to Animal Testing
The Role of Industry
1.13 The Role of Small- or Medium-Sized Enterprises in Drug Discovery
1.14 The Role of
the Pharmaceutical Industry
1.15 The Role of the Venture Capitalist
1.16 Industry?Academic Relationships
Drug Discovery: Revolution,
Decline?
1.17 Is the Biotechnology Revolution a Myth?
1.18 The Apparent Declining Efficiency of Drug Discovery
Healthcare in
the Social Context
1.19 How Much is Enough or Too Little: Assessing Healthcare Demand in Developed Countries
1.20 Health Demands
in Developing Countries
1.21 Orphan Drugs and Generics
Ethical Issues
1.22 Bioethical Issues in Medicinal Chemistry and Drug
Treatment
1.23 Ethical Issues and Challenges Facing the Pharmaceutical Industry
Funding and Regulation of Research
1.24 The
Role of Government in Health Research
1.25 Postmarketing Surveillance
Intellectual Property
1.26 Intellectual Property Rights
and Patents
| Bibliographic details |
Hardbound, 881 pages, publication date: NOV-2006
ISBN-13: 978-0-08-044514-4
ISBN-10: 0-08-044514-4
Imprint: ELSEVIER
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| Price and Ordering |
Price:
GBP 285
USD 495
EUR 325
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Last update: 5 Sep 2009
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