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With STUDENT CONSULT Online Access
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Fourth Edition
By
Bruce Carlson, MD, PhD, Professor, Department of Cell and Developmental Biology; Director, Institute of Gerontology, University of Michigan, Ann Arbor, MI
Description
This thoroughly revised 4th edition offers both clear descriptions and explanations of human embryonic development based on all the most
up-to-date scientific discoveries and understanding. Particular attention is paid to the fundamental aspects of molecular mechanisms
in development, introducing you to major families of important developmental molecules. Clinical aspects of development are covered throughout
in boxed sections of text. First-rate illustrations and Student Consult access, including online animations, complete this essential
package.
Audience
Undergraduates, and Medical Students in 1st and 2nd years
Contents
Developmental Tables
Carnegie Stages of Early Human Embryonic Development (Weeks 1-8)
Major Developmental Events During
the Fetal Period
PART I Early Development and the Fetal-Maternal Relationship
CHAPTER 1
Getting Ready
for Pregnancy
Gametogenesis
Preparation of the Female Reproductive Tract For Pregnancy
Hormonal Interaction Involved with
Reproduction in Males
CHAPTER 2
Transport of Gametes and Fertilization
Ovulation and Egg and Sperm Transport
Fertilization
CHAPTER
3
Cleavage and Implantation
Cleavage
Embryo Transport and Implantation
CHAPTER 4
Molecular Basis for Embryonic Development
Transcription Factors
Signaling Molecules
Receptor Molecules
Signal Transduction
Retinoic Acid
Developmental Genes
and Cancer
CHAPTER 5
Formation of Germ Layers and Early Derivatives
Two-Germ-Layer Stage
Gastrulation and the Three
Embryonic Germ Layers
Induction of the Nervous System
Cell Adhesion Molecules
CHAPTER 6
Establishment of the Basic
Embryonic Body Plan
Development of the Ectodermal Germ Layer
Development of the Mesodermal Germ Layer
Development of the
Endodermal Germ Layer
Basic Structure of 4-Week Old Embryo
CHAPTER 7
Placenta and Extraembryonic Membranes
Extraembryonic
Tissues
Chorion and Placenta
Placental Physiology
Placenta and Membranes in Multiple Pregnancies
CHAPTER 8
Developmental
Disorders: Causes, Mechanisms, and Patterns
General Principles
Causes of Malformations
Developmental Disturbances Resulting
in Malformations
PART II Development of the Body Systems
CHAPTER 9
Integumentary, Skeletal and Muscular
Systems
Integumentary System
Skeleton
Muscular System
CHAPTER 10
Limb Development
Initiation of Limb Development
Regulative Properties and Axial Determination
Outgrowth of Limb Bud
Morphogenetic Control of Early Limb Development
Development
of Limb Tissues
CHAPTER 11
Nervous System
Establishment of Nervous System
Early Shaping of Nervous System
Histogenesis
Within the Central Nervous System
Craniocaudal Pattern Formation and Segmentation
Peripheral Nervous System
Autonomic Nervous
System
Later Structural Changes in the Central Nervous System
Ventricles, Meninges, and Cerebrospinal Fluid Formation
Cranial
Nerves
Development of Neural Function
CHAPTER 12
Neural Crest
Origins of Neural Crest
Migrations of Neural Crest
Differentiation of Neural Crest Cells
Major Divisions of Neural Crest
CHAPTER 13
Sense Organs
Eye
Ear
CHAPTER
14
Head and Neck
Early Development of Head and Neck
Establishing the Pattern of the Craniofacial Region
Development of
Facial Region
Formation of the Teeth
Development of Pharynx and Its Derivatives
CHAPTER 15
Digestive and Respiratory
Systems and Body Cavities
Digestive System
Respiratory System
Body Cavities
CHAPTER 16
Urogenital System
Urinary
System
Genital System
Sexual Duct System
External Genitalia
CHAPTER 17
Cardiovascular System
Developmental
of Blood and the Vascular System
Developmental and Partitioning of Heart
Fetal Circulation
CHAPTER 18
Fetal Period
and Birth
Growth and Form of Fetus
Fetal Physiology
Parturition
Adaptations to Postnatal Life
Overview
Answers
to Clinical Vignettes and Review Questions
Index
| Bibliographic details |
Paperback, 560 pages, publication date: NOV-2008
ISBN-13: 978-0-323-05385-3
ISBN-10: 0-323-05385-8
Imprint: MOSBY
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Last update: 25 Nov 2009
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