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| CLINICAL IMMUNOLOGY: PRINCIPLES AND PRACTICE
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Third Edition
Edited By
Robert Rich, MD, Executive Associate Dean, Emory University, School of Medicine, Atlanta, GA, USA
Thomas Fleisher, MD, Chief, Clinical Pathology Department, National Institutes of Health, Bethesda, MD, USA
William Shearer, MD, PhD, Professor of Pediatrics and Microbiology and Immunology, Baylor College of Medicine; Chief, Allergy and Immunology Service, Texas Children's Hospital, Houston, TX, USA
Harry Schroeder, MD, PhD, Professor of Medicine and Microbiology, Division of Developmental and Clinical Immunology, University of Alabama at Birmingham, Birmingham, AL, USA
Anthony Frew
Cornelia Weyand
Description
Written and edited by international leaders in the field, this book has, through two best-selling editions, been the place to turn for
authoritative answers to your toughest challenges in clinical immunology. Now in full color and one single volume, the 3rd Edition brings
you the very latest immunology knowledge - so you can offer your patients the best possible care. The user-friendly book and the fully
searchable companion web site give you two ways to find the answers you need quickly...and regular online updates keep you absolutely
current.
Audience
Allergy, Immunology, Infectious Disease
Contents
PART 1: Fundamental Principles of the Immune Response
1 The human immune response
2 Organization of the immune
system
3 Innate immunity
4 Antigen receptor genes, gene products, and co-receptors
5 The major histocompatibility complex
6
Antigens and antigen processing
7 Antigen-presenting cells and antigen presentation
8 B-cell development and differentiation
9
T-cell development
10 Cytokines and cytokine receptors
11 Chemokines and chemokine receptors
12 Lymphocyte adhesion and trafficking
13
T-cell activation and tolerance
14 Programmed cell death in lymphocytes
PART 2: Host Defense Mechanisms and Inflammation
15
Immunoglobulin function
16 Regulatory T cells
17 Helper T-cell subsets and control of the inflammatory response
18 Cytotoxic
lymphocyte function and natural killer cells
19 Host defenses at mucosal surfaces
20 Complement and complement deficiencies
21
Phagocytes and phagocyte deficiencies
22 Mast cells, basophils and mastocytosis
23 Eosinophils and eosinophilia
PART
3: Infection and Immunity
24 Immune response to extracellular bacteria
25 Immune responses to intracellular bacteria
26
Immune responses to spirochetes
27 Immune responses to viruses
28 I mmune responses to protozoans
29 Immune responses to helminths
PART
4: Immunologic Deficiencies
30 Evaluation of the immunodeficient patient
31 Infections in the immunocompromised host
32
Development of the fetal and neonatal immune system
33 Aging and the immune system
34 Primary antibody deficiencies
35 Primary
T-cell immunodeficiencies
36 Inherited disorders of IFN-γ-, IFN-α/β-, and NF-κB-mediated immunity
37 HIV infection
and acquired immunodeficiency syndrome
38 Immunodeficiency due to congenital, metabolic, infectious,
surgical, and environmental
factors
PART 5: Allergic Diseases
39 Pathogenesis of asthma
40 Management of the asthmatic patient
41
Rhinitis and sinusitus
42 Urticaria, angiodema, and anaphylaxis
43 Allergic reactions to stinging and biting insects
44 Atopic
and contact dermatitis
45 Food allergy
46 Eosinophil-associated gastrointestinal disorders (EGID )
47 Allergic disorders of
the eye
48 Drug hypersensitivity
49 Occupational and environmental allergic disorders
PART 6: Systemic Immune Diseases
50
Mechanisms of autoimmunity
51 S ystemic lupus erythematosus
52 Rheumatoid arthritis
53 Juvenile idiopathic arthritis
54 Sj
gren's syndrome
55 Systemic sclerosis
56 Inflammatory muscle diseases
57 Spondyloarthritis
58 Small- and medium-vessel primary
vasculitis
59 Large-vessel vasculitides
60 Autoinflammatory fever syndromes
61 Antiphospholipid syndrome
PART
7: Organ Specific Inflammatory Disease
62 Immunohematologic disorders
63 Bullous diseases of the skin and mucous membranes
64
Myasthenia gravis
65 Multiple sclerosis
66 Autoimmune peripheral neuropathies
67 Immunologic renal diseases
68 Inflammation
and atherothrombosis
69 Autoimmune thyroid diseases
70 Diabetes and related autoimmune diseases
71 Immunologic lung diseases
72
Sarcoidosis
73 Immunologic ocular disease
74 Immunologic disease of the gastrointesinal tract
75 Inflammatory hepatobiliary
cirrhosis
PART 8: Neoplasia and the Immune System
76 Lymphoid leukemias
77 Lymphomas including Hodgkin
lymphoma
78 Monoclonal gammopathies
79 Tumor immunology and immunotherapy
PART 9: Transplantation
80
Concepts and challenges in transplantation: rejection,
immunosuppression and tolerance
81 Challenges and potentials of xenotransplantation
82
Hematopoietic stem cell transplantation for malignant diseases
83 Stem cell transplantation and immune reconstitution
in immunodeficiency
84
Thymic reconstitution
PART 10: Prevention and Therapy of Immunologic Diseases
85 Immunoglobulin therapy:
replacement and immunomodulation
86 Gene transfer therapy of immunologic diseases
87 Glucocorticoids
88 Nonsteroidal anti-inflammatory
drugs
89 Antihistamines
90 Immunomodulating pharmaceuticals
91 Protein kinase antagonists as therapeutic agents for immunological
and
inflammatory disorders
92 Vaccines
93 Immunotherapy of allergic disease
94 Cytokine therapy
95 Monoclonal antibodies and
fusion proteins
PART 11: Diagnostic Immunology
96 Assessment of proteins of the immune system
97 Flow
cytometry
98 Assessment of functional immune responses
99 Assessment of neutrophil function
100 Assessment of human allergic
diseases
101 Molecular methods
Apendices
1 Selected CD molecules and their characteristics
2 Laboratory
reference values
3 Chemokines
4 Cytokines
| Bibliographic details |
Hardbound, 1616 pages, publication date: APR-2008
ISBN-13: 978-0-323-04404-2
ISBN-10: 0-323-04404-2
Imprint: MOSBY
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042/409
Last update: 25 Nov 2009
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