By
Ajit Sadana, Chemical Engineering Department, University of Mississippi, MS, USA
Neeti Sadana, Jackson Memorial Hospital, The University of Miami, Miami, FL, USA
Description
Biosensors are finding increasing applications in different areas. Over the last few years the areas where biosensors may be used effectively
has increased dramatically. This book like the previous four books on analyte-receptor binding and dissociation kinetics by this author
addresses the often neglected area. The kinetics of binding and dissociation in solution to appropriate receptors immobilized on biosensor
surfaces occurs under diffusional limitations on structured surfaces. The receptors immobilized on the biosensor surface contribute
to the degree of heterogeneity on the sensor chip surface.
The fractal analysis examples presented throughout the book provide a
convenient means to make quantitative the degree of heterogeneity present on the sensor surface, and relates it to the binding and dissociation
rate coefficients. The fractal dimension is a quantitative measure of the degree of heterogeneity present on the biosensor surface.
The book emphasizes medially-oriented examples. The detection of disease-related analytes is also emphasized. The intent being that
if intractable and insidious diseases are detected earlier, they will be controlled better, eventually leading to a better prognosis.
Chapter 3 is a new chapter that emphasizes enhancing the relevant biosensor performance parameters such as sensitivity, stability, selectivity,
response time, etc.
As usual, as done in previous books by this author, the last chapter provides an update of the economics involved
in biosensors, and the difficulties encounters in starting-up a biosensor company.
Audience:
This book is suitable for academic researchers, industrial researchers, military, homeland security, other governmental and private industries.
