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THE SMALLEST BIOMOLECULES: DIATOMICS AND THEIR INTERACTIONS WITH HEME PROTEINS
The Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins
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Edited By
Abhik Ghosh, Department of Chemistry, University of Tromso, Norway

Description
This is not a book on NO biology, nor about hemoglobin, nor about heme-based sensors per se. Of course, it covers all these topics and more, but above all, it aims at providing a truly multidisciplinary perspective of heme-diatomic interactions. The overarching goal is to build bridges among disciplines, to bring about a meeting of minds. The contributors to this book hail from diverse university departments and disciplines – chemistry, biochemistry, molecular biology, microbiology, zoology, physics, medicine and surgery, bringing with them very different views of heme-diatomic interactions. The hope is that the juxtaposition of this diversity will lead to increased exchanges of ideas, approaches, and techniques across traditional disciplinary boundaries. The authors represent a veritable Who's Who of heme protein research and include John Olson, Tom Spiro, Walter Zumft, F. Ann Walker, Teizo Kitagawa, W. Robert Scheidt, Pat Farmer, Marie-Alda Gilles-Gonzalez, and many other equally distinguished scientists.

Audience
Libraries Professors and group leaders Students, postdocs

Contents
Introductory overviews Chapter 1. Mammalian myoglobin as a model for ligand understanding affinities and discrimination in heme proteins John S. Olson and Abhik Ghosh Chapter 2. A surfeit of biological heme-based sensors Marie-Alda Gilles-Gonzales and Gonzalo Gonzales Chapter 3. NO and NOx interactions with hemes Peter C. Ford, Susmita Bandyopadhyay, Mark D. Lim, Ivan M. Lorkovic Electronic structure and spectroscopy Chapter 4. CO, NO, and O2 as vbrational probes of heme protein active sites Thomas G. Spiro, Mohammed Ibrahim and Ingar Wasbotten Chapter 5. Nuclear resonance vibrational spectroscopy W. Robert Scheidt and Tim Sage Chapter 6. EPR and low-temperature MCD spectroscopy of ferrous heme nitrosyls Nicolai Lehnert Aspects of hemoglobins (except heme-NOx interactions) Chapter 7. Protoglobin and globin-coupled sensors Maqsudul Alam, Tracey Allen Keawe Freitas, Jennifer Saito, Xuehua(Ivy) Wan and Shaobin Hou Chapter 8. Neuroglobin and cytoglobin Thorsten Burmester and Tom Hankeln Chapter 9. Extreme pH sensitivity in the binding of oxygen to some fish hemoglobins: the Root effect Tom Brittain Chapter 10. Microbial hemoglobins: Structure, function and folding Tsuyoshi Egawa, Changyuan Lu, Dipanwita Batabyal, Masahiro Mukai and Syun-Ru Yeh Heme-NOx interactions Chapter 11. The reaction between nitrite and hemoglobin: The role of nitrite in hemoglobin-mediated hypoxic vasodilation Daniel B. Kim-Shapiro, Mark T. Gladwin, Rakesh P. Patel and Neil Hogg Chapter 12. Nitric oxide dioxygenase: An ancient enzymic function of hemoglobin Paul R. Gardner and Anne M. Gardner Chapter 13. Respiratory nitric oxide reductases, NorB and NorZ, of the heme?{copper oxidase type Walter G. Zumft Chapter 14. Nitric oxide reductase (P450nor) from Fusarium oxysporum Andreas Daiber, Hirofumi Shoun and Volker Ullrich Chapter 15. Nitric oxide interaction with insect nitrophorins and possibilities for the Electron configuration of the {FeNO}6 complex F. Ann Walker Chapter 16. Bioinorganic chemistry of the HNO lgand Filip Sulc and Patrick J. Farmer Selected enzymes and sensors Chapter 17. Protein-ligand interactions in mammalian nitric oxide synthase Denis L. Rousseau, David Li, Eric Y. Hayden, Haiteng Deng and Syun-Ru Yeh Chapter 18. CooA, a paradigm for gas-sensing regulatory proteins Gary P. Roberts, Robert L. Kerby, Hwan Youn and Mary Conrad Chapter 19. Soluble guanylate cyclase and its evolutionary relatives Eduardo Henrique Silva Sousa, Gonzalo Gonzalez and Marie-Alda Gilles-Gonzalez Chapter 20. Resonance Raman studies of the activation mechanism of soluble guanylate cyclase Biswajit Pal and Teizo Kitagawa Chapter 21. Insights into heme-based O2 sensing from structure-function relationships in the FixL proteins Kenton R. Rodgers, Graeme R. A. Wyllie and Gudrun S Lukat-Rodgers

Bibliographic details
Hardbound, 614 pages, publication date: DEC-2007
ISBN-13: 978-0-444-52839-1
ISBN-10: 0-444-52839-3
Imprint: ELSEVIER

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USD 240
EUR 176.95
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Last update: 25 Nov 2009
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