 |
|
| HANDBOOK OF PROCESS CHROMATOGRAPHY
| |
| | |
|
|
Development, Manufacturing, Validation and Economics
To order this title, and for more information, click here
Second Edition
By
Lars Hagel, Pharmacia Biotech AB
G nter Jagschies, GE Healthcare
Gail Sofer, GE Healthcare
Description
This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics
industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated
with recovery and purification unit operations. This book will tie that experience together for the next generation of readers.
Updates
include:
- sources and productivity
- types of products made today
- experiences in clinical and licensed products
- economics
-
current status of validation
- illustrations and tables
- automated column packing
- automated systems
New topics include:
-
the use of disposables
- multiproduct versus dedicated production
- design principles for chromatography media and filters
- ultrafiltration
principles and optimization
- risk assessments
- characterization studies
- design space
- platform technologies
- process analytical
technologies (PATs)
- biogenerics
- comparability assessments
Audience
This book is suitable for practitioners, consultants and students in Biotechnology.
Contents
Preface
Acknowledgements
1. Biopharmaceuticals Today
2. Process Capability and Production Scenarios
3. Process Design Concepts
4.
Separation Technologies
5. Analysis
6. Cleaning and Sanitization
7. Validation
8. Economics
9. Basic Properties of Peptides, Proteons,
Nucleic Acids, and Virus Particles
10. Optimization of Chromatographic Separations
11. Equipment
12. Column Packing
Appendix A. Symbols
and Definitions in Liquid Chromatography
Appendix B. Dimensionless Numbers
Appendix C. Activities for Biopharmaceutical Production from
Genetically Engineered Mammalian Cells
Appendix D. Simulations Using the Supplied Software
| Bibliographic details |
Hardbound, 382 pages, publication date: OCT-2007
ISBN-13: 978-0-12-374023-6
ISBN-10: 0-12-374023-1
Imprint: ACADEMIC PRESS
|
| Price and Ordering |
Price:
GBP 110
USD 160
EUR 129.95
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
030/303
Last update: 25 Nov 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company