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| MEDICAL APPLICATIONS OF MASS SPECTROMETRY
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Edited By
Karoly Vekey, Chemical Research Center, Hungarian Academy of Sciences, Budapest, Hungary
Andreas Telekes, National Oncology Institute, Budapest, Hungary
Akos Vertes, W.M. Keck Institute for Proteomics Technology & Applications, Washington DC, U.S.A.
Description
Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and
proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing
professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry
addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will
go a long way to help the utilization of mass spectrometry in medicine.
The book comprises five parts. A general overview is followed
by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass
spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring
various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic
tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various
fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases,
gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.
Audience
Medical professionals, practicing mass spectrometrists and students studying in these areas.
Contents
1. Introduction, Akos Vertes and Karoly Vekey
2. Basics of analytical chemistry and mass spectrometry for medical professionals, Karoly
Vekey and Andras Telekes
3. Ethical, legal, safety and scientific aspects of medical research, Andras Telekes and Karoly Vekey
4. Biomedical
sampling, Gyorgy Vaset, et al.
5. Separation methods, Karoly Vekey and Kornel Nagy
6. Mass spectrometry instrumentation and techniques,
Arpad Somogyi
7. Cheminformatics: multivariate mathematical-statistical methods for data evaluation, Karoly Heberger
8. Mass spectrometry
in proteomics, Akos Vertes
9. De novo sequencing of peptides, Alfred L. Yergey
10. Protein bioinformatics, Cathy H. Wu
11. Analysis
of complex lipidomes, Andreas Uphoff, et al.
12. Medical laboratory practice - possibilities for mass spectrometry, Olaf Bodamer
13.
Therapeutic drug monitoring, Andras Telekes, et al.
14 Mass spectrometry of infectious pathogens, Plamen A. Demirev
15. Proteomics of
viruses and their host partners, Fatah Kashanchi
16. Neonatal diagnostics, Bruno Casetta
17. Application of mass spectrometry in oncology,
John Roboz
18. Application of mass spectrometry in brain research: neurotransmitters, neuropeptides and brain proteins, Laszlo Prokai
19. The human pituitary proteome: clinical applications, Dominic M. Desiderio et al.
20. Mass spectrometry of proteinous allergens inducing
human diseases, Guenter Allmaier
21. Mass spectrometry in clinical treatment, Andras Telekes et al.
22. Biomarker discovery, Bradley
J. Thatcher
23. Molecular imaging by mass spectrometry, Richard M. Caprioli
24. Brief outlook, Karoly Vekey
| Bibliographic details |
Hardbound, 606 pages, publication date: OCT-2007
ISBN-13: 978-0-444-51980-1
ISBN-10: 0-444-51980-7
Imprint: ELSEVIER
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| Price and Ordering |
Price:
GBP 69.99
USD 120
EUR 99.95
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Last update: 27 Sep 2008
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