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| SYSTEMS BIOLOGY
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Philosophical Foundations
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Edited By
Fred Boogerd, Vrije Universiteit, Faculty of Earth and Life Sciences, Dept. of Molecular Cell Physiology, Amsterdam, The Netherlands
Frank Bruggeman, Vrije Universiteit, Faculty of Earth and Life Sciences, Department of Molecular Cell Physiology, Amsterdam, The Netherlands
Jan-Hendrik Hofmeyr, University of Stellenbosch, Faculty of Science, Department of Biochemistry, Matieland, South Africa
H.V. Westerhoff, Vrije Universiteit, Faculty of Earth and Life Sciences, Dept. of Molecular Cell Physiology, Amsterdam, The Netherlands
Description
Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination
of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry.
Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is
entitled to its own scientific foundations rather than being dominated by existing philosophies.
Audience
Computational biologists, Molecular biologists, Cellular biologists, Systems biologists, Bioinformaticians, Philosophers of Science, Philosophers of Biology
Contents
Introduction
1. Towards philosophical foundations of Systems Biology: Introduction
Research programs of Systems Biology
2. The methodologies
of Systems Biology
3. Methodology is Philosophy
4. How can we understand metabolism?
5. On Building Reliable Pictures with Unreliable
Data: an Evolutionary and Developmental Coda for the New Systems Biology?
Theory / models
6. Mechanism and mechanical explanation
in cell biology
7. Theories, Models, and Equations in Systems Biology
8. All models are wrong.......some more than others
9. Data
without models merging with models without data
Organization in biological systems
10. The biochemical factory that autonomously fabricates
itself: a systems-biological view of the living cell
11. A systemic approach to the origin of biological organization
12. Organization
and biological mechanisms: organized to maintain autonomy
13. The disappearance of function from 'self-organizing systems'
Conclusion
14. Afterthoughts as foundations for Systems Biology
| Bibliographic details |
Hardbound, 360 pages, publication date: MAR-2007
ISBN-13: 978-0-444-52085-2
ISBN-10: 0-444-52085-6
Imprint: ELSEVIER
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Price:
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USD 130
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Last update: 22 Sep 2009
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