Edited by
Satinder Ahuja, Ahuja Consulting, Calabash, NC, USA
Henrik Rasmussen, Global Analytical Development, Johnson and Johnson Pharmaceutical Research and Development, Raritan, NJ, USA
Description
High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring
changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final
drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses
these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC,
column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample
preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective.
HPLC
Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development
chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.
Included in series
Separation Science and Technology
Audience:
For researchers, analysts, managers, and regulators of the pharmaceutical industry
