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| SYNTHESIS OF ESSENTIAL DRUGS
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By
Ruben Vardanyan, University of Arizona, Tucson, Arizona, USA
Victor Hruby, University of Arizona, Tucson, Arizona, USA
Description
This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more
than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature
of drug synthesis.
The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in
a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology
curriculum in a manner useful to chemists.
Practically every chapter begins with an accepted brief definition and description of
a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed
by a detailed description of methods for their synthesis.
Of the thousands of drugs existing on the pharmaceutical market, we mainly
discuss generic drugs that are included in the WHO?s "Essential List of Drugs."
For practically all of the 700+ drugs described
in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.
This
book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas
of biologically active compounds and the synthesis of medicinal drugs.
Audience
Chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students
Contents
1. General Anesthetics
2. Local Anesthetics
3. Analgesics
4. Hypnotics and Sedatives
5. Anxiolitics (Tranquilizers)
6. Antipsycotics (Neuroleptics)
7. Antidepressants
8. Central Nervous System Stimulants
9. Antiepileptics
10.
Anti-Parkinson Drugs
11. Adrenegic (Sympatomimetic) Drugs
12. Adrenoblocking Drugs
13. Cholinomimetics
14. Anticholinergic
Drugs
15. Muscle Relaxants
16. Antihistamine Drugs
17. Cardiac Glycosides and Other Inotropes
18. Drugs for Tachyarrhytmias
19. Antianginal Drugs
20. Agents Used in Hyperlipoproteinemia
21. Diuretics
22. Antihypertensive Drugs
23. Drugs
for Treating of Pulmonary Diseases
24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics
25. Thyroid and Parathyroid
Drugs
26. Insulin and Synthetic Hypoglycemic Agents
27. Corticosteroids
28. Female Sex Hormones
29. Male Sex Hormones
and Anabolics
30. Antineoplastic Agents
31. Immunopharmacologic Drugs
32. Antibiotics
33. Antimicrobials
34.
Antimicobacterials
35. Antifungal Drugs
36. Antiviral Drugs
37. Antiprotozoal Drugs
38. Antihelmint Drugs
| Bibliographic details |
Hardbound, 634 pages, publication date: MAR-2006
ISBN-13: 978-0-444-52166-8
ISBN-10: 0-444-52166-6
Imprint: ELSEVIER
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| Price and Ordering |
Price:
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USD 275
EUR 216.95
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Last update: 10 Sep 2009
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