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NEUROBIOLOGY OF ADDICTION
Neurobiology of Addiction
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By
George Koob, Molecular and Integrative Neurosciences Department , The Scripps Institute, La Jolla, California, USA
Michel Le Moal, Physiopathologie du Comportement Institut National de la Santé et de la Recherche Médicale Université Victor Ségalen Bordeaux 2 Bordeaux, France

Description
Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts – a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature.

Audience
Graduate students and professionals in neuroscience, neurology, psychology.

Contents
1. What is Addiction. 2. Animal Models of Drug Addiction. 3. Psychostimulants. 4. Opioids. 5. Alcohol. 6. Nicotine. 7. Cannabinoids. 8. Imaging. 9. Neurobiological Theories of Addiction. 10. Drug Addiction: Transition from Neuroadaptation to Pathophysiology.

Bibliographic details
Hardbound, 504 pages, publication date: NOV-2005
ISBN-13: 978-0-12-419239-3
ISBN-10: 0-12-419239-4
Imprint: ACADEMIC PRESS

Price and Ordering
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USD 155
EUR 129.95
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Last update: 5 Sep 2009
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