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| LANDMARK PAPERS IN CLINICAL CHEMISTRY
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Edited By
Richard M. Rocco, Department of Biology, San Francisco State University, California, USA
Description
This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original
inventors and discoverers. Introductory comments by the editor help place the works within the historical context.
Landmark
Papers addresses:
*The origin of the home pregnancy test available today in every drugstore
*The woman who invented a billion
dollar technology, refused to patent it and went on to win a Nobel Prize
*The scientists who worked on the US Government?s crash program
at the start of WWII to find a substitute for the malaria drug quinine
*The blood test used to monitor the effectiveness of cholesterol
lowering drugs that today are taken by over 20 million patients
*The graduate student who invented a technology for testing for infectious
diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide
*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine
*The development of the glucose meter
used by diabetics up to six times a day to monitor their metabolic control
Audience
Students and workers in the clinical laboratory field; Teachers in the clinical laboratory field; Clinical Chemists; Clinical Pathologists;
Medical Laboratory Technologists; Industries that have commercialized the technologies (i.e., Abbott, Beckman, Pharmacia, etc...)
Contents
Preface
Section I IMMUNOASSAY TECHNOLOGY
RIA (Radioimmunoassay)
1. Yalow, R.S., Berson, S.A. (1960: Assay of plasma insulin in man.
FPIA
(Fluorescence Polarization Immunoassay)
2. Dandliker, W.B., Feigen, G.A. (1961): Quantification of the antigen-antibody reaction by
the polarization of fluorescence.
CPB (Competitive Protein Binding)
3. Murphy, B.E.P., Pattee, C.J. (1964): Determination of thyroxine
utilizing the property of protein-binding.
ELISA (Enzyme-Linked Immunosorbent Assay)
4. Engvall, E., Perlmann, P. (1972): Enzyme-linked
immunosorbent assay, ELISA. III.
EMITa (Enzyme Immunoassay Technique)
5. Rubenstein, K.E., Schneider, R. S., Ullman, E.F. (1972): "Homogeneous"
enzyme immunoassay.
Section II THERAPEUTIC DRUG MONITORING (TDM)
Bromide
6. Wuth, O. (1927): Rational bromide treatment.
Sulfonamides
7. Bratton, A.C., Marshall, E.K., Jr., (1939): A New Coupling Component for Sulfanilamide Determination.
Quinine and Quinidine
8.
Brodie, B.B., Udenfriend, S. (1943): The estimation of quinine in human plasma with a note on the estimation of quinidine.
Digoxin
9. Smith, T.W., Butler, V.P., Haber, E. (1969): Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay.
Theophylline
10. Thompson, R.D., Nagasawa, H.T., Jenne, J.W. (1974): Determination of theophylline and its metabolites in human urine
and serum by high-pressure liquid chromatography.
Section III ENZYMOLOGY
ALP (Alkaline Phosphatase, EC 3.1.3.1))
11. Bessey, O.A.,
Lowry, O.H., Brock, M.J. (1946): A method for the rapid determination of alkaline phosphatase with five cubic millimeters of serum.
AST
(Aspartate Aminotransferase, EC 2.6.1.1)
12. Karmen, A., Wroblewski, F., LaDue, J.S. (1955): Transaminase activity in human blood.
CK (Creatine Kinase, EC 2.7.3.2)
13. Mercer, D.W. (1974): Separation of tissue and serum creatine kinase isoenzymes by ion-exchange
column chromatography.
Section IV SPECIFIC ANALYTES
Colorimetric Analysis with the Duboscq
14. Folin, O., Wu, H. (1919): A system
of blood analysis.
Blood Gases by Manometer
15. Van Slyke, D.D. (1924): The determination of gases in blood and other solutions by
vacuum extraction and manometric measurement. I.
Bilirubin, Total and Direct With the Filter Photometer
16. Malloy, H.T., Evelyn, K.A.
(1937): The determination of bilirubin with the photometric colorimeter.
Proteins by the Biuret Reaction
17. Gornall, A. G., Bardawill,
C. J., David, M. M. (1949): Determination of serum proteins by means of the Biuret reaction.
Methods for Pediatric and Neonatal Samples
18. Natelson, S. (1951): Routine use of ultramicro methods in the clinical laboratory.
Enzymatic Glucose
19. Huggett, A.S., Nixon,
D.A. (1957): Use of glucose oxidase, peroxidase, and o-dianisidine in determination of blood and urinary glucose.
HCG (Human Chorionic
Gonadotropin) by Immunoassay
20. Wide, L., Gemzell, C.A. (1960): An immunological pregnancy test.
Hemoglobin A1c
21. Rahbar, S. (1968):
An Abnormal Hemoglobin in Red Cells of Diabetics.
LDL (Low Density Lipoprotein) Cholesterol by Calculation
22. Friedewald, W.T., Levy,
R.I., Fredrickson, D.S. (1972): Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the
preparative ultracentrifuge.
Section V INSTRUMENTATION AND TECHNIQUES
Paper Electrophoresis
23. Durrum, E.L. (1950): A microelectrophoretic
and microionophoretic technique.
Automated Analyzer
24. Skeggs, L.T. (1957): An automatic method for colorimetric analysis.
Enzymatic
Glucose, Dry Reagents on Pads
25. Free, A.H., Adams, E.C., Kercher, M.L., Free, H. M., Cook, M. H., (1957): Simple Specific Test for
Urine Glucose.
Blood Gas Elelctrodes
26. Severinghaus, J., Bradley, A.F. (1958): Electrodes for blood pO2 and pCO2 determination.
Specific Ion Electrodes
27. Friedman, S.M., Nakashima, M. (1961): Single sample analysis with the sodium electrode.
Centrifugal Analyzer
28. Anderson, N.G. (1969): Analytical techniques for cell fractions. XII. A multiple-cuvet rotor for a new microanalytical system.
Immunoassays on Membranes
29. Glad, C., Grubb, A.O. (1978): Immunocapillary migration- A new method for immunochemical quantitation.
Western Blots
30. Towbin, H., Stachelin, T., Gordon, J. (1979): Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose
sheets: Procedure and some applications.
Capillary Electrophoresis (CE)
31. Jorgenson, J.W., Lukacs, K. DeA. (1981): Zone electrophoresis
in open-tubular glass capillaries.
Section VI CHEMOMETRICS
Quality Control Charts
32. Levey, S., Jennings, E.R. (1950): The Use
of Control Charts in the Clinical Laboratory.
Interferences in Analytical Accuracy
33. Caraway, W. (1962): Chemical and Diagnostic Specificity
of Laboratory Tests.
Predictive Value Theory
34. Vecchio, T.J. (1966): Predictive value of a single diagnostic test in unselected populations.
Standards and Calibrators
35. Radin, N. (1967): What is a standard?
Test Kits
36. Barnett, R.N., Cash, A.D., Junghams, S.P. (1968):
Performance of "kits" used for clinical chemical analysis of cholesterol.
Section VII MOLECULAR DIAGNOSTICS
Biochemical Genetics
37. Pauling, L., Itano, H.A., Singer, S.J., Wells., I.C. (1949): Sickle cell anemia, a molecular disease.
Nucleic Acid Probes
38.
Hyypia, T., Jalava, A., Larsen, S.H., Terho, P., Hukkanene, V. (1985): Detection of Chlamydia trachomatis in clinical specimens by nucleic
acid spot hybridization.
Microarrays
39. Maskos, U., Southern, E.M. (1992): Oligonucleotide hybridizations on glass supports: A novel
linker for oligonucleotide synthesis and hybridization properties of oligonucleotide synthesized in situ.
Acknowledgments
Author Index
Subject Index
| Bibliographic details |
Hardbound, 522 pages, publication date: NOV-2005
ISBN-13: 978-0-444-51950-4
ISBN-10: 0-444-51950-5
Imprint: ELSEVIER
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