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| HIGH THROUGHPUT ANALYSIS FOR EARLY DRUG DISCOVERY
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To order this title, and for more information, click here
Edited By
James Kyranos, ArQule, Inc., Woburn, MA, USA
Description
This book offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving
the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate
types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages. The description of
various combinatorial and high-throughput parallel synthesis techniques provide a relevant point of entry for synthetic chemists who
need to set up appropriate characterisation methods for his/her organisation. This is an invaluable resource for all organic and analytical
chemists in the pharmaceutical, agrochemical, and biotechnology fields who are either involved in, or beginning to investigate combinatorial
techniques to increase overall efficiency and productivity.
Contents
High Throughput Analysis of Combinatorial Libraries Encoded with Electrophoric Molecular Tags, Adolor Corporation (J. Guo et al.).
Analysis of a Combinatorial Library Synthesized Using a Split-and-pool Irori MicroKan Method for Development and Production, Boehringer
Ingelheim Pharmaceuticals, Inc. (H. Lee, C.R. Sarko).
High-Throughput Mass Spectrometry-Flow Injection Analysis, Procter and Gamble
Pharmaceuticals (K.L.
Morand).
High-Throughput Flow-Injection ESI and APCI Mass Spectrometry for Combinatorial Chemistry: Automated
Acquisition and Interpretation for Multi-Sprayer Low-Resolution and FTMS High-Resolution Exact-Mass Measurements, Wyeth Research (C.
Truebenbach et al.).
Purity and Quantity Determination of Parallel Synthesis Compound Libraries, ArQule, Inc. (J. Delaney et al.).
High-Throughput Parallel LC/MS/ELSD of Combinatorial Libraries Using the Eight-Channel LCT System With MUX Technology,
Nereus Pharmaceuticals Inc and University of California, San Diego (P.W. Davis, M.C. Griffith).
Purification and Analysis of Parallel
Libraries, Albany Molecular (C. Garr).
Screening Single Bead Combinatorial Libraries Using Capillary HPLC and MALDI-TOF-MS, National
Research Council (D.A. Voller et al.).
The Role of NMR in the Analysis of Chemical Libraries, Bristol Meyers Squibb (S.W.
Gerritz, A. M. Sefler).
| Bibliographic details |
Hardbound, 204 pages, publication date: SEP-2004
ISBN-13: 978-0-12-431165-7
ISBN-10: 0-12-431165-2
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
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GBP 127
EUR 149.95
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Last update: 5 Sep 2009
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