Edited by
F. Rosenow, Zentrum fur Nervenheilkunde, Klinik für Neurologie, Philipps-Universitat Marburg, Germany
Hans Luders, MD, PhD, Department of Neurology, Cleveland Clinic Foundation, Cleveland, OH
Description
The objective of resective epilepsy surgery is the complete resection or complete disconnection of the epileptogenic zone, which is defined
as the area of cortex indispensable for the generation of clinical seizures. Ideally this aim should be accomplished without damaging
the "eloquent" cortex. The epileptogenic zone can currently not be measured directly. Therefore, a variety of diagnostic tools such as
analysis of seizure semiology, neurophysiological techniques, functional testing as well as structural and functional neuroimaging are
used to indirectly define the location and boundaries of the epileptogenic zone. These diagnostic methods define different cortical zones
(symptomatogenic zone, irritative zone, ictal onset zone, stimulation induced seizure zone, functional deficit zone, and the epileptogenic
lesion) which all are a more or less precise index of the location and extent of the epileptogenic zone. The ability to precisely define
these zones is essential to best appreciate the topography of the epileptogenic zone.
This volume provides an up to date and
complete overview of the methods used in clinical neurophysiology as well as structural and functional imaging used to delineate these
different zones currently as well as methods currently applied as research tools which may evolve to be used in clinical practice in
the future.
Included in series
Handbook of Clinical Neurophysiology
Audience:
Epileptologists, neurologists, clinical neurophysiologists, neuroscientists, physiologists.
