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 | THE HUMAN GENOME
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A User's Guide
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Second Edition
By
Julia Richards, University of Michigan, Ann Arbor, MI
R. Scott Hawley, Stowers Institute for Medical Research, Kansas City, MO
Description
This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on
society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is
becoming a commonplace scientific discussion on the evening news. Join authors Julia Richards and Scott Hawley as they examine the biological
foundations of humanity, looking at the science behind the sensation and the current and potential impact of the study of the genome
on our society.
The Human Genome, Second Edition is ideal for students and non-professionals, but will also serve as a fitting
guide for the novice geneticist by providing a scientific, humanistic, and ethical frame of reference for a more detailed study of genetics.
Contents
Acknowledgments
Preface
SECTION 1: The Basics of Heredity
1. Slaying Molecular Dragons: Brenda?s Tale
2. The Answer in
a Nutshell: Genes, Proteins, and the Basis of Life
3. Mendel and the Concept of the Gene
4. Human Mendelian Genetics
5. One Man?s Trait
Is Another Man?s Disease
SECTION 2: The Central Dogma of Molecular Biology
6. DNA: The Genetic Alphabet
7. The Central
Dogma of Molecular Biology: How Genes Encode Proteins
8. Splicing the Modular Gene
9. Orchestrating the Human Genome
SECTION
3: How Chromosomes Move
10. So What are Chromosomes Anyway?
11. How Cells Move Your Genes Around
12. Passing Genes Between Generations
13. The Chromosomal Basis of Heredity
SECTION 4: Mutation
14. Absent Essentials and Monkey Wrenches
15. How We Detect
Mutations
16. We Are All Mutants
17. What Constitutes Normal?
18. Mutations in Mammoth Genes
19. Expanded Repeat Traits
SECTION
5: Genes, Chromosomes, and Sex
20. The X and Y Chromosomes: The Odd Couple
21. Genetics of Sex, Gender, and Orientation
22.
Aneuploidy: When Too Much or Too Little Counts
SECTION 6: Breaking the Rules
23. Imprinting
24. Imitating Heredity:
One Trait, Many Causes
SECTION 7: The Human Genome Landscape
25. The Human Genome Project
26. There?s Cloning and Then
There?s Cloning
27. The Human Genome Sequence
28. Finding Genes in the Human Genome
SECTION 8: Complex and Heterogeneous Traits
29. Genotype Phenotype Correlations
30. How Complex Can It Get?
31. Quantitative Traits
32. The MAOA Gene: Is There a Genetic Basis for
Criminality?
33. The Multiple-Hit Hypothesis: The Genetics of Cancer
SECTION 9: Genetic Testing and Therapy
34. Genetic
Testing and Screening
35. Magic Bullets: The Potential for Gene Therapy
SECTION 10: Fears, Faith, and Fantasies
36.
Heroes Among Us
37. Fears, Faith, and Fantasies
Credits
Index
| Bibliographic details |
Paperback, 480 pages, publication date: OCT-2004
ISBN-13: 978-0-12-333462-6
ISBN-10: 0-12-333462-4
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
EUR 52.95 USD 64.95 GBP 45
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Last update: 7 Sep 2009
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