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| THE GENETICS OF CANCER
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Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation
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By
Gajanan Sherbet, Cancer Research Unit, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, U.K.
M. Lakshmi, Cancer Research Unit, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, U.K.
Description
Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into
the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation
of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes
in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians,
and researchers working in the fields of cancer biology, genetics, and molecular biology.
Audience
Graduates, research scientists, and research clinicians in cancer biology, oncology, pathology, genetics, molecular biology, and biomedicine in general.
Contents
Preface.
Acknowledgement.
Introduction.
Clonal Evolution of Metastasis.
Inefficiency of the Metastatic Process.
Tumor Growth and Metastatic
Potential.
Cell Cycle Regulation and Metastasis.
Apoptosis in Tumor Growth and Metastasis.
Angiogenesis in Cancer.
Cell Surface Glycoproteins
and Their Receptors.
Proteinases and Their Inhibitors in Cancer Invasion.
Oncogenes and Cancer Metastasis.
Developmental Genes and Their
Putative Tumor Suppressor Function.
Tumor Suppressor Genes.
Metastasis Suppressor Genes.
Dominant Metastasis Associated Genes.
Epilogue.
References.
| Bibliographic details |
Hardbound, 338 pages, publication date: JUN-1997
ISBN-13: 978-0-12-639875-5
ISBN-10: 0-12-639875-5
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
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USD 165
EUR 118.95
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Last update: 7 Sep 2009
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