By
Robert Weinberger, CE Technologies, Chappaqua, New York, U.S.A.
Description
In the 1980s, capillary electrophoresis (CE) joined high-performance liquid chromatography (HPLC) as the most powerful separation technique
available to analytical chemists and biochemists. Published research using CE grew from 48 papers in the year of commercial introduction
(1988) to 1200 in 1997. While only a dozen major pharmaceutical and biotech companies have reduced CE to routine practice, the applications
market is showing real or potential growth in key areas, particularly in the DNA marketplace for genomic mapping and forensic identification.
For drug development involving small molecules (including chiral separations), one CE instrument can replace 10 liquid chromatographs
in terms of speed of analysis. CE also uses aqueous rather than organic solvents and is thus environmentally friendlier than HPLC. The
second edition of
Practical Capillary Electrophoresis has been extensively reorganized and rewritten to reflect modern
usage in the field, with an emphasis on commercially available apparatus and reagents. This authoritative and very comprehensible treatment
builds on the author's extensive experience as an instructor of short courses for the American Chemical Society and for industry.
Audience:
Analytical chemists and biochemists, technicians, graduate students, and advanced undergraduates.
