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| BIOCHEMISTRY OF REDOX REACTIONS
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Edited By
Bernard Testa, University Hospital Centre, Lausanne, Switzerland
John Caldwell
Description
Surpassing the 1976 book by Testa and Jenner, Drug Metabolism: Chemical and Biochemical Aspects (Dekker), this informative,
up-to-date text includes the following features, unavailable elsewhere: First in a set of books to provide a comprehensive coverage of
drug metabolism; Opening chapter provides a general introduction to the complete set of books; Other chapters cover reaction mechanisms,
catalytic cycles, regio- and stereoselectivities, types of substrates, reactivity of intermediates, and drug-enzyme interactions; Extensive
detailed diagrams of reaction pathways and chemical structures
Audience
Graduate students and researchers in universities and pharmaceutical companies working on drug metabolism.
Contents
Xenobiotic Metabolism: The Global View.
Xenobiotic Metabolism: The Biochemical View.
Dehydrogenation of Alcohols and Aldehydes, Carbonyl
Reduction.
The Nature and Functioning of Cytochromes P450 and Flavin-Containing-Monooxygenases.
Carbon Oxidations Catalyzed by Cytochromes
P450.
Monooxygenase-Catalyzed N-C Cleavage.
Monooxygenase-Catalyzed Oxidation of Oxygen- and Sulfur-Containing Compounds.
Oxidative Dehalogenation
and Dealkylation of Organometallics.
Oxidations Catalyzed by Various Oxidases and Monooxygenases.
Reactions Catalyzed by Peroxidases.
Oxidation of Mercury, Silicon, Phosphorus, Arsenic, Selenium, and Halogens.
Reductions Catalyzed by Cytochrome P450 and Other Oxidoreductases.
Various Enzymatic and Nonenzymatic Reactions.
Conclusion and Outlook.
| Bibliographic details |
Hardbound, 471 pages, publication date: OCT-1994
ISBN-13: 978-0-12-685391-9
ISBN-10: 0-12-685391-6
Imprint: ACADEMIC PRESS
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| Price and Ordering |
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GBP 144.99
EUR 171.95
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Last update: 4 Sep 2009
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