 |
|
| CONTEMPORARY ENZYME KINETICS AND MECHANISM, 3RD EDITION
| |
| | |
|
|
Reliable Lab Solutions
To order this title, and for more information, click here
Second Edition
Daniel Purich, University of Florida, Gainesville, U.S.A.
Description
Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches
are equally useful in examining the action of newly discovered enzymes and therapeutic agents.Contemporary Enzyme Kinetics and
Mechanism, Second Edition presents key articles from Volumes 63, 64, 87, and 249 of Methods in Enzymology.
The chapters describe the most essential and widely applied strategies. A set of exercises and problems is included to facilitate mastery
of these topics.
The book will aid the reader to design, execute, and analyze kinetic experiments on enzymes. Its emphasis on enzyme
inhibition will also make it attractive to pharmacologists and pharmaceutical chemists interested in rational drug design.
Of the seventeen
chapters presented in this new edition, ten did not previously appear in the first edition.
Audience
Students and professionals in biochemistry, biophysics, molecular biology, pharmacology, and pharmaceutical chemistry.
Contents
C.A. Fierke and G.G. Hammes, Transient Kinetic Approaches to Enzyme Mechanisms.R.D. Allison and D.L. Purich, Practical
Considerations in the Design of Initial Velocity Enzyme Assays.C.Y. Huang, Derivation ofInitial Velocity and Isotope Exchange
Rate Equations.F.B. Rudolph and H.J. Fromm, Plotting Methods for Analyzing Enzyme Rate Data.B. Mannervik, Regression
Analysis, Experimental Error, and Statistical Criteria in the Design and Analysis of Experiments for Discrimination between Rival Kinetic
Models.K.E. Neet, Cooperactivity in Enzyme Function: Equilibrium and Kinetic Aspects.B.F. Cooper and F.B. Rudolph,
Product Inhibition Applications.H.J. Fromm, Reversible Enzyme Inhibitors as Mechanistic Probes.A. Radzicka and R. Wolfenden,
Transition State and Multisubstrate Analog Inhibitors.B.V. Plapp, Application of Affinity Labeling for Studying Structure and
Function of Enzymes.R.B. Silverman, Mechanism-Based Enzyme Inactivators.D.L. Purich and R.D. Allison, Isotope Exchange
Methods for Elucidating Enzymic Catalysis.L.S. Mullins and F.M. Raushel, Positional Isotope Exchange as a Probe of Enzyme Action.
W.W. Cleland, Isotope Effects: Determination of Enzyme Transition State Structure.B.J. Bahnson and J.P. Klinman, Hydrogen
Tunneling in Enzyme Catalysis.B.V. Plapp, Site-Directed Mutagenesis: A Tool for Studying Enzyme Catalysis.D.L. Purich,
Selected Exercises and Problems in Modern Enzyme Dynamics.
| Bibliographic details |
Paperback, 541 pages, publication date: AUG-1996
ISBN-13: 978-0-12-568052-3
ISBN-10: 0-12-568052-X
Imprint: ACADEMIC PRESS
|
| Price and Ordering |
Price:
GBP 79
USD 115
EUR 105
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
092/900
Last update: 30 Oct 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company