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GENETIC MAPPING OF DISEASE GENES
Genetic Mapping of Disease Genes

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Edited By
Ivar-Harry Pawlowtzki, Institut for Humangenetik, Universitat Munster, Germany
J. Edwards
Elizabeth Thompson, University of Washington, Seattle, U.S.A.

Description
A state-of-the-art reference, Genetic Mapping of Disease Genes presents a detailed account of the new methodical approaches to gene mapping. It provides completely up-to-date information and comprehensive coverage of research in this field, and includes contributions from the leading experts. The book gives a broad overview of the genetic mapping involved in inherited diseases and discusses the shortcomings of established mapping procedures. The book will be essential reading for all researchers and postgraduate research students in molecular genetics, clinical genetics, and molecular biology, but also those involved in ophthalmology, public health, medical statistics, and mathematics.

Audience
Researchers and postgraduate research students in genetics with emphasis on human molecular genetics, clinical genetics, molecular biology, epidemiological genetics, and biochemistry. Individuals in the fields of opthamology, pediatrics, gynecology, psychiatry, hearing research, public health, tropical medicine, blood banking, medical statistics, and mathematics.

Contents


Introduction and History:
J.H. Edwards, Introduction.A.W.F. Edwards, The Early History of the Statistical Estimation of Linkage.

Linkage in Dominant, Recessive, and Polygenic Disease:
N.E. Morton and P. Lio, Oligogenic Linkage and Map Integration.J. Ott, Genetic Mapping in Complex Disorders.J.H. Edwards, Recessive Disease and Allelic Association.T. Grimm, Mutation-Selection-Equilibria, Genetic Models, and Linkage Analysis.D. Stephens and C.A.B. Smith, Simple Likelihood and Probability Calculations for Linkage Analysis.

Bibliographic details
Hardbound, 288 pages, publication date: AUG-1997
ISBN-13: 978-0-12-232735-3
ISBN-10: 0-12-232735-7
Imprint: ACADEMIC PRESS

Price and Ordering
Price:
GBP 87
USD 141
EUR 102.95
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Last update: 4 Sep 2009
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