 |
|
| EXCITATORY AMINO ACIDS
| |
| | |
|
|
Clinical Results with Antagonists
To order this title, and for more information, click here
Edited By
Paul Herrling, Sandoz Research Institute, Berne, Switzerland
Description
Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety
of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity,
emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as potential
drugs for central nervous system disorders. Excitatory Amino Acids is the first book entirely dedicated to the results
of human testing of modulators of excitatory amino acid neurotransmitters.
Audience
Neuroscientists; neuropharmacologists in the pharmaceutical industry, and neurologists.
Contents
M. Schmutz, A. Arthur, H. Faleck, G. Karlsson, A. Kotake, L. Landwicki, L. LaRue, S. Markabi, D. Murphy, M. Powell, and D. Sauer,
Selfotel.P. Herrling et al., D-CPPene (SDZ EAA-494) A Competitive NMDA Antagonist: Pharmacology and Results in Humans.J.D.
Kristensen, Intrathecal Administration of a Competitive NMDA Receptor Antagonist for Pain Treatment.A.G. Knapp, L.I. Matthews,
and E.R. Gamzu, Clinical Experience with the NMDA Ion-Channel Blocker, Aptiganel Hydrochloride (CEROSTAT).M.-L. Maccecchini,
Development of ACPC: A Partial Agonist of the Glycine Site on the NMDA Receptor.Carter et al., Ifenprodil and Eliprodil: Neuroprotective
NMDA Receptor Antagonists and Calcium Channel Blockers.D. Lodge and D.D. Schoepp, 3S, 8aR-6-[2-(1(2)H-tetrazole-5-y)ethyl]
Decahydroisoquinoline-3-carboxylic Acid (LY293558) and Its Racemate (LY215490): A Selective and Competitive AMPA/Kainate Receptor Agonist.
L. Nordholm, M. Sheardown, and T. Honore, The NBQX Story.E. Louvel, Riluzole in Amytrophic Lateral Sclerosis.G.C.
Plamer and J.B. Hutchinson, Preclinical and Clinical Aspects of Remacemide Hydrochloride.
| Bibliographic details |
Hardbound, 156 pages, publication date: JAN-1997
ISBN-13: 978-0-12-546820-6
ISBN-10: 0-12-546820-2
Imprint: ACADEMIC PRESS
|
| Price and Ordering |
Price:
USD 220
GBP 132.99
EUR 156.95
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
095/945
Last update: 4 Sep 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company