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 | DRUG-DRUG INTERACTIONS: SCIENTIFIC AND REGULATORY PERSPECTIVES, 43
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To order this title, and for more information, click here
J. August, John Hopkins University; Department of Pharmacology, Baltimore, Maryland, U.S.A.
Albert Li, In Vitro Technologies, Inc., and University of Maryland Technology Center, Baltimore, Maryland, U.S.A.
Ferid Murad, University of Texas Medical School, Houston, U.S.A.
M. Anders, University of Rochester; Department of Pharmacology, New York, U.S.A.
Joseph Coyle, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, U.S.A.
Included in series
Advances in Pharmacology,
Description
DrugDrug Interactions is a comprehensive review of the scientific and regulatory perspectives of drugdrug
interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals
in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding
of drugdrug interactions, the prediction of drugdrug interaction potential of new drugs, and the avoidance of clinically
significant drugdrug interaction in patients.
Audience
Professionals in the pharmaceutical industry, health care industry, and governmental regulatory agencies. Students and researchers in
the areas of pharmacology, toxicology, pharmacokinetics, and medicine.
Contents
J. Collins, Foreword.A.P. Li, Preface.A.P. Li, Overview: Scientific Basis of Pharmacokinetic Drug-Drug Interactions.
F.P. Guengerich, Role of Cytochrome P450 Enzymes in Drug-Drug Interactions.J.M. Sauer, E.R. Stine, L. Gunawardhana, D.A.
Hill, and I.G. Sipes, The Liver as a Target for Chemical-Chemical Interactions.A.D. Rodrigues and S.L. Wong, Applications
of Human Liver Microsomes in Metabolism-Based Drug-Drug Interactions.A.P. Li, Applications of Human Hepatocytes as an Experimental
System for the Evaluation of Pharmacokinetic Drug-Drug Interactions.J.L. Ferrero and K. Brendal, Liver Slices as a Model in
Drug Metabolism and Drug-Drug Interactions.C.L. Crespi and B.W. Penman, The Use of cDNA Expressed Human Cytochrome P450 Enzymes
to Study Potential Drug-Drug Interactions.G.L. Kedderis, Pharmacokinetics of Drug Interactions.T.N. Thompson, Experimental
Models for Evaluating Enzyme Induction Potential of New Drug Candidates in Animals and Man and a Strategy for Their Use.J.D. Balian,
Metabolic Drug-Drug Interactions: Perspective from U.S. FDA Medical and Clinical Pharmacology Reviewers.M. Jurima-Romet, Drug
Interactions: Perspectives of the Canadian Directorate.
| Bibliographic details |
Hardbound, 304 pages, publication date: OCT-1997
ISBN-13: 978-0-12-032944-1
ISBN-10: 0-12-032944-1
Imprint: ACADEMIC PRESS
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| Price and Ordering |
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GBP 135.99 USD 225 EUR 160.95
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Last update: 3 Oct 2009
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