By
S.C. Moldoveanu, Brown & Williamson Tobacco Corporation, 2600 Weaver Rd, Macon, GA 31217, USA
V. David, Department of Analytical Chemistry, University of Bucharest, Sos. Panduri 90, Sect.5, Bucharest, Romania
Description
Sample preparation is an essential step in many analyses. This book approaches the topic of sample preparation in chromatography in a
methodical way, viewing it as a logical connection between sample collection and analytical chromatography. Providing a guide for choosing
the appropriate sample preparation for a given analysis, this book describes various ways to process the sample, explaining the principle,
discussing the advantages and disadvantages, describing the applicability to different types of samples, and showing the fitness to specific
chromatographic determinations.
The first part of the book contains an overview of sample preparation showing its relation to sample
collection and to the core chromatographic analysis. The second part covers procedures that do not use chemical modifications of the
analyte and includes methods for sample dissolution, concentration and cleanup designed mainly for modifying the initial matrix of the
sample. This part starts with conventional separations such as filtration and distillation and finishes with more advanced techniques
such as solid phase extraction and electroseparations. The third part gives a description of the chemical modifications that can be
performed on a sample either for fractionation purposes or to improve a specific property of the analyte. This part includes derivatizations,
polymer chemical degradations, and pyrolysis.
Included in series
Journal of Chromatography Library
Audience:
For a wide range of readers, including specialists in analytical chemistry and beginners in this field.
