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| ORGANIC SYNTHESIS THEORY AND APPLICATIONS, 5
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Volume 5
To order this title, and for more information, click here
By
T. Hudlicky, Department of Chemistry, University of Florida, P.O. Box , Gainesville, FL 32611-7200, USA
Included in series
Organic Synthesis: Theory and Applications, 5
Description
Volume 5 in this series spans a variety of topics including terpene synthesis, amino acid synthesis, and combinatorial methods for generation of structural diversity.
The first chapter has been contributed by Trond Hansen and Professor Yngve Strenstr?m of the Agricultural
University of Norway, and surveys naturally occurring cyclobutanes. As well as providing a review of representative syntheses and synthetic
strategies for the introduction of cyclobutane into target molecules, the number of rings contained in the natural product is also discussed
in logical order.
The following chapter, written by Professor Timothy Brocksom, his wife Ursula, and a number of co-workers from
the Federal University of São Carlos, surveys the synthesis of higher terpenes by the use of Diels-Alder reaction. A useful review
of the current literature in this field is provided, together with 79 references and footnotes.
The third chapter, written by Michael
G. Natchus and Xinrong Tian of Procter & Gamble Pharmaceuticals, covers recent advances in the synthesis of unnatural amino acids.
Three of the major asymmetric methods are discussed and grouped according to the chemistry involved.
The fourth and final chapter
has been contributed by Professor Dennis Wright of the University of Florida, and other co-workers. A review of the combinatorial chemistry
methods currently available for lead discovery in pharmaceutical research is provided in this chapter, as well as discussions on the
methods based on natural products and an overview of the complexity building techniques.
Audience
For synthetic organic chemists, industrial chemists, pharmaceutical companies, and university libraries.
Contents
Chapter headings
. Preface. Naturally occurring cyclobutanes (T.V. Hansen, Y. Stenstrøm). Diels-alder reactions
in the synthesis of higher terpenes (T.J. Brocksom et al.). The asymmetric synthesis of unnatural α-amino acids as building
blocks for complex molecular synthesis (M.G. Natchus, X. Tian). The role of organic synthesis in the generation of molecular diversity
(D.L. Wright et al.). Biographical sketches of the contributors. Index.
| Bibliographic details |
Hardbound, 276 pages, publication date: DEC-2001
ISBN-13: 978-0-080-44037-8
ISBN-10: 0-080-44037-1
Imprint: ELSEVIER
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| Price and Ordering |
Price:
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USD 281
GBP 169.99
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Last update: 4 Sep 2009
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