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By
P.U. Giacomoni, Clinique Laboratories, 125 Pinelawn Rd, Melville, NY 11747, USA
Included in series
Comprehensive Series in Photosciences, 3
Description
"Sun Protection in Man" looks at the beneficial and harmful effects of solar radiation. The physiological consequences of sun
exposure have been systematically studied starting at the end of the nineteenth century and we now have accumulated knowledge about how
Caucasian and Asian skins reacts to solar radiation. The chemical effects of solar ultraviolet radiation have been analyzed with particular
emphasis during the second half of the twentieth century. Research on micro-organisms has allowed us to understand the mechanisms of
UV-induced mutagenesis and photosensitization. Studies with laboratory rodents have opened the path to the understanding of UV-induced
immune-depression, carcinogenesis, photo-damage and photo-aging. The results of these studies have enabled other scientists to investigate
the same phenomena in human organs such as the skin and the eye. UV radiation damages hair, as well. The present knowledge in these fields
is summarized in some of the chapters of this monograph.
Mass phenomenon in Europe with the generalization of summer vacations which
were a consequence of social reforms introducing the concept of "paid vacations". This created a need for protection and opened a market
for sunscreens.
This monograph is concerned with sun protection as a whole and is not just "another book on sunscreens". Nonetheless,
in these days of general concern, it is important to learn about the efficiency of sunscreens. Several authors discuss how to reduce
the number of impinging photons and explain why sunscreens seem to offer less protection than expected. Guidelines are given on how to
use sunscreens in everyday life, which are expressed rigorously though clearly, for access to the common reader.
Our knowledge on
the relationship between sun and humans is at the early stages of development. Industrial and commercial activities are concerned by
the development of this knowledge, and rules have been and will be promulgated to guarantee efficacy and safety of sun-products. It is
hoped that this monograph will be of interest to the scholar, the layman and the legislator.
Audience
For chemists, biochemists and dermatologists with an interest in photobiology, pharmacy and photomedicine.
Contents
Chapter headings. Preface. Historical Perspective. Women (and men) and sun in ancient times (P.U. Giacomoni). The Advantages of Sunlight.
A perspective on the beneficial effects of moderate exposure to sunlight: bone health, cancer prevention, mental health and well being
(M. F. Holick). Clinical Effects of Solar Radiation. The negative effects of solar radiation: a clinical overview (F. Urbach). The effects
of sunlight on the skin of Asians (J.H. Chung). Effects of solar radiation on the human immune system (M. Norval). The negative effects
of solar and artificial irradiation: photoaging of the skin, its clinical appearance and underlying mechanisms (M. Wlaschek et al.).
The epidemiology of solar radiation and skin cancer (B.K. Armstrong, A. Kricker). Hazards of sunlight exposure to the eye (J.E. Roberts).
Photodegradation of human hair (S.B. Ruetsch et al.). Molecular Effects of Solar Radiation. UV damage to nucleic acid components
(J.L. Ravanat et al.). Lipid photo-oxidative damage in biological membranes: reaction mechanisms, cytotoxic consequences and
defense strategies (A. W. Girotti). Photo-oxidation of proteins and its consequences (M.J. Davies, R.J.W. Truscott). Cellular And Physiological
Consquences Of Solar Radiation. Erythema: a link between UV-induced DNA damage, cell death and clinical effects? (M. Heenen). UV radiation,
mutations and oncogenic pathways in skin cancer (F.R. de Gruijl, H.J. van Kranen). Modulation of gene expression by solar ultraviolet
radiation (S. Basu-Modak, R.M. Tyrrell). Cytotoxicity and morphological endpoints of exposure to UV: cultured cells as a model system
(E. Straface et al.). Drug-induced skin phototoxicity: lessons from the fluoroquinolones (N.K. Gibbs). Natural Defence against
Solar Radiation. Pigmentation of human skin after UV (A. Young). Nucleotide excision repair of UV-radiation induced photolesions in human
cells (A.A. Van Zeeland et al.). Natural defence against ultraviolet radiation. The role of heat shock proteins (F. Trautinger).
p53 Protein and the response of human skin to UV (D. Decraene et al). Effect of solar radiation on detoxification mechanisms
in the skin (S.K. Katiyar et al.). Artificial Protection Against Solar Radiation: Blocking The Photons. Eye protection from
sunlight damage (J. Gallas, M. Eisner). Artificial protection against solar radiation - fabrics
(B.M.H. Driscoll). Self tanning (G. Monfrecola,
E. Prizio). Photochemical and photophysical properties of sunscreens
(A. Cantrell et al.). Sunscreens: use and misuse
(B.L.
Diffey). Sunscreens: practical applications
(D. Orentreich et al.). Artificial Protection Against Solar Radiation: Stimulating
Self Protection. Protection against solar radiation-protective properties of antioxidants
(W. Stahl, H. Sies). Systemic photoprotection.
Dietary intervention and therapy (H.S. Black, L.E. Rhodes). Enhancement of repair of UV damage in humans (C. Yarosh). Boosting the immune
system (F.M. Strickland). Skin pigmentation enhancers (D.A. Brown). Metabolic consequences of solar radiation and boosters of intermediate
metabolism (E.L. Jacobson et al). How Can Science Provide Help To Everyday's Life? An Example. Sunlamps and sunbeds: safety
and regulatory issues (W.H. Cyr, S.A. Miller). Physics of our environment: solar radiation spectra. The physics of solar radiation (H.
Seidliz).
| Bibliographic details |
Hardbound, 780 pages, publication date: JUL-2001
ISBN-13: 978-0-444-50839-3
ISBN-10: 0-444-50839-2
Imprint: ELSEVIER
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| Price and Ordering |
Price:
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GBP 253
EUR 298.95
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Last update: 30 Nov 2009
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