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| INTERORGANELLAR SIGNALING IN AGE-RELATED DISEASE, 7
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Edited By
M.P. Mattson, Laboratory of Neurosciences, National Institute on Aging, Gerontology Research Center, Baltimore, MD, USA
Included in series
Advances in Cell Aging and Gerontology, 7
Description
Collectively, the chapters in this work will provide the reader with novel insight into the inter-relationships of the function of different
organelles in the sequences of events that lead to cellular dysfunction and degeneration in the aging human population. The chapters
are rich in information for cell and molecular biologists pursuing studies of the different diseases covered. In addition, the clinician
will find value in understanding mechanisms underlying age-related disease as such an understanding will lead to novel therapeutic approaches
for an array of age-related diseases.
Contents
Preface.
Peroxisomal alterations in aging and age-related disease (J. Youssef, M. Badr).
Perturbed calcium homeostasis in neurodegenerative
disorders (M.P. Mattson).
Mitochondrial dysfunction in diabetes mellitus (M.F. Bauer, S. Hofmann, K.-D. Gerbitz).
Mitochondrial signaling
and cancer (T.J. Preston, G. Singh).
Molecular chaperones and age-related degenerative disorders (A.J.L. Macario, E. Conway de Macario).
The role of telomerase in age-related degenerative disease and cancer (M. Fossel).
Mitochondrial oxidative stress and metabolic alterations
in neurodegenerative disorders (J.N. Keller, G.W. Glazner).
Importance of proteasome-mediated proteolysis and alterations of the ubiquitin/proteasome
pathway in cancer cells (V.J. Spataro, C.J. Norbury).
Contributors' addresses.
| Bibliographic details |
Hardbound, 284 pages, publication date: APR-2001
ISBN-13: 978-0-444-50495-1
ISBN-10: 0-444-50495-8
Imprint: ELSEVIER
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| Price and Ordering |
Price:
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EUR 91.95
USD 128
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Last update: 4 Sep 2009
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