Edited By
Y. Shoenfeld, Department of Medicine, Research Unit of Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel
R.C. Kennedy, Department of Microbiology and Immunology, The University of Oklahoma, Health Science Center, Oklahoma City, OK 73190, USA
S. Ferrone, Department of Microbiology and Immunology, New York Medical College, Valhalla, NY 10595, USA
Description
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies
is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part
focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer
and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
