Edited by
D.E. Levy, Glycomed Inc., California, USA
C. Tang, SUGEN Inc., California, USA
Description
In recent years
C-glycoside chemistry has been one of the main topics in carbohydrate chemistry, not only because of the synthetic
challenges posed, but also because
C-glycosides have the potential to serve as carbohydrate analogues resistant to metabolic
processes. Consequently, this class of compounds is currently receiving much interest as a potential source of therapeutic agents for
clinical use. This book provides a broad coverage of the various synthetic methods available for the preparation of
C-glycosides,
and illustrates the interesting breadth of connections between carbohydrate chemistry and modern general synthetic organic chemistry
by including topics such as transition-metal catalysis, radical chemistry, cycloaddition and rearrangement processes. In addition, in
the final chapter of the book, the syntheses of C-di and trisaccharides reported through 1994 are reviewed. This well organised account
of the synthetic chemistry in this field will prove to be very valuable to a wide range of researchers and advanced students, both as
an introduction to the topic and for reference.
Included in series
Tetrahedron Organic Chemistry
Audience:
For organic chemists, medicinal chemists, graduate students and academic and industrial researchers.