Edited by
Robert Blanchard
D. Blanchard
Guy Griebel
David Nutt, DM FRCP FRCPsych FmedSci , Edmond J Safra Chair in Neuropsychopharmacology, Imperial College London, UK
Description
This Handbook brings together and integrates comprehensively the core approaches to fear and anxiety. Its four sections: Animal models;
neural systems; pharmacology; and clinical approaches, provide a range of perspectives that interact to produce new light on these important
and sometimes dysfunctional emotions. Fear and anxiety are analyzed as patterns that have evolved on the basis of their adaptive functioning
in response to threat. These patterns are stringently selected, providing a close fit with environmental situations and events; they
are highly conservative across mammalian species, producing important similarities, along with some systematic differences, in their
human expression in comparison to that of nonhuman mammals. These patterns are described, with attention to both adaptive and maladaptive
components, and related to new understanding of neuroanatomic, neurotransmitter, and genetic mechanisms. Although chapters in the volume
acknowledge important differences in views of fear and anxiety stemming from animal vs. human research, the emphasis of the volume is
on a search for an integrated view that will facilitate the use of animal models of anxiety to predict drug response in people; on new
technologies that will enable direct evaluation of biological mechanisms in anxiety disorders; and on strengthening the analysis of anxiety
disorders as biological phenomena.
Included in series
Handbook of Behavioral Neuroscience
Audience:
Neuroscientists, Psychologists, Psychopharmacologists, Clinical Psychologists and Psychiatrists
