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| CLINICAL PHARMACOLOGY AND THERAPEUTICS OF HYPERTENSION, 25
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Handbook of Hypertension Series
To order this title, and for more information, click here
By
Gordan McInnes, BSc, MD, FRCP, FFPM, FAHA, Division of Cardiovascular and Medical Sciences, Gardiner Institute, Western Infirmary, Glasgow, UK
Included in series
Handbook of Hypertension,
Description
This volume reviews comprehensively the present understanding of the clinical pharmacology and therapeutics of currently available antihypertensive
agents. As fewer new molecules are entering development it becomes increasingly important to utilise existing drugs in a way that exploits
their full potential through a greater understanding of their molecular biology and pharmacogenomics.
Contents
Section I: General considerations:
Classification of antihypertensive drugs and pharmacological considerations.
Interaction of antihypertensive drugs with mechanisms of blood pressure regulation. Antihypertensive drugs: pharmacokinetics, pharmacodynamics,
metabolism, side effects and drug interactions. Antihypertensive drugs: hemodynamic effects.
Section II: Diuretics:
Thiazides
and loop diuretics. Aldosterone antagonists
Section III: Centrally acting drugs:
Methyldopa and imidazolone
agonists.
Section IV: Vasodilator drugs:
Alpha-blocking drugs. Calcium channel blockers. Potent vasodilators.
Section
V: Beta-blocking agents:
Beta-adrenoceptor blocking drugs.
Section VI: Drugs acting on the renin-angiotensin
system:
Angiotensin converting enzyme inhibitors. Angiotensin receptor blockers. Vasopeptidase inhibitors.
Section
VII: Future prospects:
Novel agents in development.
Section VIII: Clinical trials:
The
evidence-base for treatment of hypertension.
Section IX: Therapeutic strategies:
Combination therapy.
Sequential monotherapy.
Section X: Special patient groups:
Pregnancy. The elderly. Hypertension and diabetes.
Ethnic considerations in hypertension.
| Bibliographic details |
Hardbound, 608 pages, publication date: APR-2008
ISBN-13: 978-0-444-51757-9
ISBN-10: 0-444-51757-X
Imprint: ELSEVIER
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999/999
Last update: 10 Sep 2009
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