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 | CELLULAR AND MOLECULAR NEUROPHYSIOLOGY
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To order this title, and for more information, click here
Third Edition
By
Constance Hammond, Directeur de Recherches, INMED U29 INSERM, Marseille, France
Description
This third edition is the new, thoroughly revised edition of the only current, established and authoritative text focusing on the cellular
and molecular physiology of nerve cells. Previously titled Cellular and Molecular Neurobiology, the new title better reflects
this focus. The book is hypothesis driven rather than just presenting the facts, and the content is firmly based on numerous experiments
performed by the top experts in the field. While the book does cover the important facts, it also presents the background for how researchers
arrived at this knowledge to provide a context for the field. It teaches not only how excitable cells work in detail, but also how to
construct and conduct intelligent research experiments. This book promotes a real understanding of the function of nerve cells that is
useful for practicing neurophysiologists and students in a graduate-level course on the topic alike.
Audience
Neurophysiologists, neurobiologists, neurologists, as well as graduate-level courses on neurophysiology.
Contents
Part I – Neurons: Excitable and Secretory Cells that Establish Synapses.
Chapter 1: Neurons
Chapter 2: Neuron ?Glial Cell Cooperation
Chapter 3: Ionic Gradients, Membrane Potential and Ionic Currents
Appendix 3.1: The active transport of ions by pumps and transporters
maintain the unequal distribution of ions
Appendix 3.2: The passive diffusion of ions through an open channel
Appendix 3.3: The Nernst
equation
Chapter 4: The Voltage-Gated Channels of Na+ Action Potentials
Appendix 4.1: Current clamp recording
Appendix 4.2: Voltage clamp
recording
Chapter 5: The Voltage-Gated Channels of Ca+2Action Potentials: Generalization
Appendix 5.1: Fluorescence measures of intracellular
Ca2+ concentration
Appendix 5.2: Tail currents
Chapter 6: The Chemical Synapses
Appendix 6.1: Neurotransmitters, agonists and antagonists
Appendix 6.2: Identification and Localization of Neurotransmitters and their Receptors
Chapter 7: Neurotransmitter Release
Appendix 7.1:
Quantal nature of neurotransmitter release
Appendix 7.2: The probabilistic nature of neurotransmitter release (the neuromuscular junction
as a model)
Part 2 – Ionotropic and Metabotropic Receptors in Synaptic Transmission and Sensory Transduction.
Chapter 8: The Ionotropic
Nicotinic Acetycholine Receptors
Appendix 8.1: The neuronal nicotinic receptors
Chapter 9: The Ionotropic GABAA Receptor
Appendix 9.1:
Mean time and mean burst duration of the GABAA single-channel current
Appendix 9.2: Non-invasive measurements of membrane potential
and of the reversal potential of the GABAA current using cell-attached recordings of single channels
Chapter 10: The Ionotropic Glutamate
Receptors
Chapter 11: The Metabotropic GABAB Receptors
Chapter 12: The Metabotropic Glutamate Receptors
Part 3 – Somato-Dendritic Processing
and Plasticity of Postsynaptic Potentials.
Chapter 13: Somato-Dendritic Processing of Postsynaptic Potentials
I: Passive Properties of
Dendrites
Chapter 14: Subliminal Voltage-Gated Currents of the Somato-Dendritic Membrane
Chapter 15: Somato-Dendritic Processing of
Postsynaptic Potentials
II: Role of Subliminal Depolarizing Voltage-Gated Currents
Chapter 16: Somato-Dendritic Processing of Postsynaptic
Potentials
III: Role of High Voltage-Activated Depolarizing Currents
Chapter 17: Firing Patterns of Neurons
Chapter 18: Synaptic Plasticity
Appendix 18.1: Depolarization of induced suppression of inhibition (DSI)
Part 4 – The Adult Hippocampal Network.
Chapter 19: The Adult
Hippocampal network
Chapter 20: Maturation of the Hippocampal Network
| Bibliographic details |
Hardbound, 416 pages, publication date: FEB-2008
ISBN-13: 978-0-12-374127-1
ISBN-10: 0-12-374127-0
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
USD 79.95 EUR 56.95 GBP 47.99
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Last update: 25 Nov 2009
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