Edited By
J. McIntosh
Description
Recent advances in the imaging technique electron microscopy (EM) have improved the method, making it more reliable and rewarding, particularly
in its description of three-dimensional detail. This book will help biologists from many disciplines understand modern EM and the value
it might bring to their own work. The book’s five sections deal with all major issues in EM of cells: specimen preparation, imaging
in 3-D, imaging and understanding frozen-hydrated samples, labeling macromolecules, and analyzing EM data. Each chapter was written
by scientists who are among the best in their field, and some chapters provide multiple points of view on the issues they discuss. Each
section of the book is preceded by an introduction, which should help newcomers understand the subject. The book shows why many biologists
believe that modern EM will forge the link between light microscopy of live cells and atomic resolution studies of isolated macromolecules,
helping us toward the goal of an atomic resolution understanding of living systems.
Included in series
Methods in Cell Biology
Audience:
Researchers in various fields of biology who utilize electron microscopy.
