Edited By
Scott Hemby
Sabine Bahn
Description
The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities
and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along
with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides
are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression
may not directly equate with protein expression. There are many potential applications for proteomics in neuroscience: determination
of the neuro-proteome, comparative protein expression profiling, post-translational protein modification profiling and mapping protein-protein
interactions, to name but a few.
Functional Genomics and Proteomics in Clinical Neuroscience will comment on all of
these applications, but with an emphasis on protein expression profiling. This book combines the basic methodology of genomics and proteomics
with the current applications of such technologies in understanding psychiatric illnesses.
Included in series
Progress in Brain Research
Audience:
Neuroscientists, neurologists, geneticists.
