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CHURCHILL'S IN CLINICAL PRACTICE SERIES: ACUTE CORONARY SYNDROMES
Churchill's In Clinical Practice Series: Acute Coronary Syndromes
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By
Richard Katz, MD, FACC, Professor of Medicine, Director of Division of Cardiology, The George Washington University School of Medicine, Washington, DC, USA
Henry Purcell, MB, PhD, Senior Fellow in Cardiology, Royal Brompton Hospital, London, UK

Included in series
Churchill's In Clinical Practice,

Description
This title, which contains contributions from Europe in addition to the USA and Canada, distills and organizes the maze of clinical data on the diagnosis, risk stratification, treatment, and prevention of acute coronary syndromes. The book discusses pragmatically how to treat NSTEMI and STEMI, looking at some of the oldest drugs available, such as aspirin, through to the new thrombin inhibitors, lytics and such like. The book flags up many of the developments in the fields of inflammation, infection, reversal of endothelial dysfunction, thrombolysis versus primary angioplasty and so forth, and presents the evidence to support the rapidly evolving guidelines.

Contents
Foreword Professor Kim Fox

Definitions: epidemiology and prognosis

Pathophysiology
- plaque rupture
- inflammation and ACS
- platelets and the coagulation system

Diagnosis
- clinical signs and symptoms
- chest pain evaluation
- resting 12-lead ECG
- cardiac enzymes and biomarkers
- risk stratification
- inflammatory and other prognostic markers
- exercise testing
- radionuclide testing
- coronary angiography

Prevention of ACS

Current management
- site-based algorithms
- rationale for specific treatments
- oral antiplatelet therapies (aspirin and thienopyridines)
- anti-thrombin therapies
(heparin)
(low molecular weight heparin)
(direct thrombin inhibitors)

Intravenous anti-platelet therapy
glycoprotein IIb/IIIa inhibitors

Anti-ischaemic therapies
- nitrates
- beta blockers
- calcium blockers
- nicorandil

Medical revascularisation

Disease modifying agents
- statins in ACS
- ACE inhibitors
- Do anti-infectives play a role?

Treatment of acute myocardial infarction (STEMI)

Clinical Cases
Appendix 1 – Drug tables
Appendix 2 – Useful websites and addresses
References
Index

Bibliographic details
Paperback, 168 pages, publication date: MAR-2006
ISBN-13: 978-0-443-10296-7
ISBN-10: 0-443-10296-1
Imprint: CHURCHILL LIVINGSTONE


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Last update: 10 Sep 2009
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