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 | PHYSICS IN NUCLEAR MEDICINE
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Third Edition
By
Simon Cherry, PhD, Professor, Department of Biomedical Engineering, University of California - Davis, Davis, CA
James Sorenson, PhD, Emeritus Professor of Medical Physics, University of Wisconsin - Madison, Madison, WI
Michael Phelps, PhD, Norton Simon Professor, Chair, Department of Molecular and Medical Pharmacology, Chief, Division of Nuclear Medicine, UCLA School of Medicine, Los Angeles, CA
Description
Experts in their fields provide up-to-date, comprehensive information on the physics underlying modern nuclear medicine and imaging using
radioactively labeled tracers. They examine every aspect of the field--from basic atomic physics through radioactivity, isotope production,
interaction of radiation with matter, radiation detection, and imaging systems. Examples are presented with solutions worked out in step-by-step
detail, illustrating important concepts and calculations.
Audience
Primary: Radiology and Nuclear Medicine Residents; Secondary: Cardiologists, Oncologists
Contents
CHAPTER 1: What is Nuclear Medicine
a. Fundamental Concepts b. The Power of Nuclear Medicine c. Historial Overview d.
Current Practice of Nuclear Medicine e. The Role of Physics in Nuclear Medicine
CHAPTER 2: Basic Atomic and Nuclear
Physics
a. Quantities and Units b. Radiation c. Atoms d. Nucleur
CHAPTER 3: Modes of Radioiactive
Decay
a. General Concepts b. Chemistry and Radioactivity c. Decay by Emission d. Isomeric Transition and Internal
Conversion e. Electron Capture and Decay f. Positron and Decay g. Competitive and EC Decay h. Decay by Emission and Nuclear
Fission i. Decay Modes and the Line of Stability j. Sources of Information on Radionuclides
CHAPTER 4: Decay of
Radioactivity
a. Activity b. Exponential Decay c. Methods for Determining Decay Factors d. Image-Frame Decay Corrections e.
Specific Activity f. Decay of a Mixed Radionuclide Sample g. Parent-Daughter Decay
CHAPTER 5: Isotope Production
and Tracer Synthesis
a. Reactor-Produced Radionuclides b. Accelerator-Produced Radionuclides c. Radionuclide Generators d.
Equations for Radionuclide Production e. Radionuclides for Nuclear Medicine f. Radiiopharmaceuticals for Clinical Applications
CHAPTER
6: Interaction of Radiation with Matter
a. Interactions of Charged Particles with Matter b. Charged-Particle Ranges c.
Passage of High-Energy Photons Through Matter d. Attenuation of Photon Beams
CHAPTER 7: Radiation Detectors
a.
Gas-filled Detectors b. Semi-conductor Detectors c. Scintillation Detectors
CHAPTER 8: Electronic Instrumentation
for Radiation Detection
a. Preamplifiers b. Amplifers c. Pulse-Height Analyzers d. Time-to-Amplitude Converters e.
Digital Counters and Ratemeters f. Coincidence Units g. High-Voltage Power Supplies h. Nuclear Instrument Modules i. Cathode
Ray Tube j. Oscilloscopes k. Computer Monitors
CHAPTER 9: Nuclear Counting Statistics
a. Types of Measurement
Error b. Nuclear Counting Statistics c. Propagation of Errors d. Applications of Statistical Analysis e. Statistical Tests
CHAPTER
10: Pulse Height Spectrometry
a. Basic Principles b. Spectrometry with Nal c. Spectrometry with other Detectors
CHAPTER
11: Problems in Radiation Detection and Measurement
a. Detection Efficiency b. Problems in the Detection and Measurement
of Particles c. Deadtime d. Qualtity Assurance for Radiation Measureme Systems
CHAPTER 12: Counting Systems
a.
Nal Well Counter b. Counting with Conventional Nal Detectors c. Liquid Scintillation Counters d. Gas-filled Detectors e.
Semiconductor Detector Systems f. In Vivo Counting Systems
CHAPTER 13: The Gamma Camera: Basic Principles
a.
General Concepts of Radionuclide Imaging b. Basic Principles of the Anger Camera
CHAPTER 14: Gamma Camera Performance
Characteristics
a. Basic Performance Characteristics b. Detector Limitations: Nonuniformity and Nonlinearit c. Design
and Performance Characteristics of Parellel-Hole Collinators d. Performance Characteristics of Converging, Diverging and Pinhole Collimators e.
Measurements of Camera Performance
CHAPTER 15: Image Quality in Nuclear Medicine
a. Basic Methods for Characterizing
and Evaluating Image Quality b. Spatial Resolution c. Contrast d. Noise e. Detectability and Observer Performance Studies
CHAPTER
16: Tomographic Reconstruction in Nuclear Medicine
a. General Concepts, Notation and Terminology b. Backprojection and
Fourier-Based Techniques c. Image Quality in FT and FBP Techniques d. Iterative Reconstruction Algorithms e. Reconstruction
of Fan-Beam and Cone-Beam Data
CHAPTER 17: Single Photon Emission Computed Tomography
a. SPECT Systems b.
Practical Implementation of SPECT c. Performance Characteristics of SPECT Systems d. Clinical Applications of SPECT
CHAPTER
18: Positron Emission Tomography
a. Annihilation Coincidence Detectioin b. PET Detector and Scanner Designs c. Dataa
Acqusition for PET d. Data Corrections and Quantitative Aspects of PET e. Clinical and Research Applications of PET
CHAPTER
19: Computers in Nuclear Medicine
CHAPTER 20: Internal Radiation Dosimetry
CHAPTER 22:
Radiation Safety and Health Physics
CHAPTER 23: Summary
| Bibliographic details |
Hardbound, 544 pages, publication date: AUG-2003
ISBN-13: 978-0-7216-8341-6
ISBN-10: 0-7216-8341-X
Imprint: SAUNDERS
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999/999
Last update: 30 Nov 2009
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