Description This volume draws together studies on the diverse group of calcium-activated chloride channels (CaCCS) in one comprehensive format. The
characteristics of CaCCs identified in a number of different systems are described by experts in the field. Channels discussed include
those described in cardiac, neuronal, endothelial and epithelial systems, in addition to sections on the CaCC of Xenopus Oocytes
and the newly identified family of CLCA proteins.
Audience
Cell biologists, biochemists, molecular biologists, electrophysiologists, biophysicists, membrane transport physiologists, tumor and cell
biologists, researchers working on epithelial chloride transport, and researchers working on cardiac and somatosensory physiology.
Contents Dedication
Preface
SECTION 1: CaCCs in XENOPUS OOCYTES
The Endogenous Calcium-Activated Cl Channel in Xenopus
Oocytes: A Physiologically and Biophysically Rich Model System.
Ca2+-Inactivated Cl- Channels in Xenopus laevis Oocytes.
SECTION 2: Ca2+-ACTIVATED Cl- CURRENTS IN EXCITABLE TISSUES
A Ca2+-Activated Anion Channel in the Sarcoplasmic Reticulum
of Skeletal Muscle.
Physiological Role of the Ca2+ - activated Cl- Current in Mammalian Heart.
Recent Advances on the Properties and
Role of Ca2+-activated Chloride Currents in Smooth Muscle.
The Calcium-activated Chloride Conductance in Olfactory Receptor Neurons.
Ca2+-activated Cl- Channels as Ca2+-Sensors with Particular Reference to the Modulation of Neuronal Excitability.
Determination of Intracellular
Chloride Concentration in Dorsal Root Ganglion Neurons by Fluorescence Lifetime Imaging.
SECTION 3: Ca2+-ACTIVATED Cl- CURRENTS
IN NON-EXCITABLE TISSUES
Calcium-activated Cl- Conductance in the Airway Epithelium.
Ca2+-activated Cl- Currents in Salivary
and Lacrimal Glands.
Properties and Role of Calcium-activated Chloride Channels in Pancreatic Duct Cells.
Calcium-Mediated Chloride Secretion
in the Intestinal Epithelium: Significance and Regulation.
Renal Expression of Ca2+-activated Cl- Channels.
Calcium-dependent Anion Secretion
in Endometrial Epithelial Cells.
Calcium-activated Chloride Channels in Vascular Endothelial Cells..
Regulation of Calcium-activated
Chloride Channels by Inositol 3,4,5,6-Tetrakisphosphate.
SECTION 4: THE CLCA FAMILY
Discovery and Cloning of the CLCA
Gene Family.
Electrophysiology of the CLCA Family.
CLCA Adhesion in Site-Specific Cancer Metastasis.
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