Edited by
M.E. Gershwin, University of California, Clinical Division of Rheumatology, School of Medicine, Davis, CA, USA
M.E. Gershwin, University of California, Clinical Division of Rheumatology, School of Medicine, Davis, CA, USA
Pier-Luigi Meroni, Department of Immunology, University of Milan, Italy
Y. Shoenfeld, Department of Medicine 'B', The Research Center of Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel
Description
Autoimmune diseases are characterized by the occurrence of antibodies reacting with self constituents of the body. This exciting new reference
is an exhaustive review of the main autoantibodies identified up to now, with particular emphasis on those autoantibodies that display
a clinical value. Each chapter is focussed on a single family of autoantibodies by reviewing their historical notes, definition, origin
and source(s) of the antigen(s) recognized, genetic associations, pathogenic mechanisms that are mediated, method(s) of detection and
clinical utility (disease prevalence/association, diagnostic value, sensitivity and specificity, prognostic value). An ideal reference
for anyone involved in the field of autoimmune diseases.
Audience:
Physicians and students in Internal Medicine, Rheumatology, Clinical Immunology, Hematology, Endocrinology, Gastroenterology, Neurology,
Nephrology, and Dermatology. Also of interest to those working in companies involved in selling diagnostic assays for autoimmune
disorders.