 |
|
| ATLAS OF EARLY ZEBRAFISH BRAIN DEVELOPMENT
| |
| | |
|
|
A Tool for Molecular Neurogenetics
To order this title, and for more information, click here
By
Thomas Mueller, CNRS, Institute of Neurobiology A. Fessard, Gif-sur-Yvette, France
Mario F. Wullimann, CNRS, Institute of Neurobiology A. Fessard, Gif-sur-Yvette, France
Description
The Atlas of Early Zebrafish Brain Development is the first neuroanatomical expression atlas of important genetic and
immunohistochemical markers of a vertebrate model system. In-situ hybridized and immunostained preparations of complete series of brain
sections reveal markers of the fundamental stages in the life history of neuronal cells (proliferation/determination, migration and neuronal
differentiation) in very high quality preparations and photographic plates. Early brain organization is vividly demonstrated and local
variations in brain development are shown in a holistic view.
This book represents a key reference and interpretation matrix to analyze
expression domains of genes involved in Zebrafish brain development and neurogenesis and thus represents a milestone in this research
area. There is simply no alternative source for combined neuroanatomical and gene expression data in the Zebrafish at this level of detail.
The book introduces the reader to the field and shows principles of vertebrate brain development and neurogenesis. It will also be of
great value to investigators of other model organisms such as frog, chick and mouse.
Audience
Developmental Biologists, Neuroscientists, Molecular Biologists working primarily in laboratories, but will also appeal to students. A
must have book for libraries with Developmental Neuroscience customers.
Contents
Preface.
Vertebrate Central Nervous System Development.
Chapter 1. Introduction.
1. Vertebrate central nervous system development.
1.1. Introductory remarks: the order of the universe.
1.2. Major developmental stages of the vertebrate neural tube.
1.3. Functional
brain architecture: mammalian examples.
1.4. Teleostean (anamniote) brain development in perspective.
1.5. The approach of this book.
Atlas of Cellular Markers in Zebrafish Neurogenesis.
Chapter 2. Atlas.
2. Atlas of cellular markers in zebrafish neurogenesis.
2.1. Choice and characterization of molecular markers.
2.2. Technical details.
2.3. The end of embryonic life (2 days): outset of secondary
neurogenesisnotch1a neurog1 neurod Hu-proteins.
2.4. The early larva (3 days): the emergence of brain subdivisions PCNA neurod
Hu-proteins
2.5. The late larva (5 days): increasing differentiation BrdU Hu-proteins.
Interpretation of data - how to
use the atlas.
Chapter 3. Analysis.
3. Interpretation of data - how to use the atlas
.
3.1. General and local dynamics of neurogenesis.
3.2. The BrdU saturation label.
3.3. How to fit in new gene expressions Zash1a/Zash1b.
Comparison of fish, frog, chick
and mouse brains.
Chapter 4. Model Systems.
4. Comparison of fish, frog, chick and mouse brains.
.
4.1. Expression of basic Helix-Loop-Helix
(bHLH) genes supports similar forebrain organization in vertebrates.
4.2. Additional early genes distinguish pallium and subpallium in
vertebrates.
4.3. Comparable early diencephalic gene expression in vertebrates.
4.4. Chick and frog forebrain patterns.
Literature Cited.
Index.
| Bibliographic details |
Hardbound, 0 pages, publication date: JUN-2005
ISBN-13: 978-0-444-51738-8
ISBN-10: 0-444-51738-3
Imprint: ELSEVIER
|
| Price and Ordering |
Price:
GBP 114.99
USD 190
EUR 135.95
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
095/945
Last update: 30 Nov 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company