Edited by
George Vande Woude, Director, Van Andel Research Institute, Grand Rapids, MI, USA
George Klein, Karolinska Insitutet, Stockholm, Sweden
Description
This volume of
Advances in Cancer Research begins with a review by M. Roussel of the key effectors of cytokine and growth
factor signaling to the cell cycle block. P 53 and how it controls the cell cycle, genomic stability, and apoptosis are reviewed by M.R.A.
Mowat. The third chapter, by T.S. Lewis and colleagues, discusses the effect of MAP kinase cascades as examples of signal transduction
mechanisms in signaling pathways. In Chapter 4, Sozi
et al. Review the frequent abnormalities found in the
FHIT gene
in a variety of cancer-derived cell lines. Volume 74 concludes with an overview by J.J. Hsuan and co-workers of the cellular functions
of PtdlnsP2 and the regulation of its biosynthesis.
Included in series
Advances in Cancer Research
Audience:
Graduate students and researchers in developmental, molecular, and cell biology as well as genetics, zoology, agriculture, and neuroscience.
