Edited by
S. Gordon, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
Description
The present volume focuses on microbial invasion strategies of pathogen uptake. An accompanying volume (Vol. 5) in the series presents
the phagocytic process from the viewpiont of the host cell.
This field of study is growing rapidly after a somewhat slow start over
recent decades. This collection of invited chapters attempts to reflect current research and brings together cell biologists, microbiologists,
and immunologists wiht disthemes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors
intracellular parasitism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage and
some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early
events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or
pahtogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is
becoming increasingly clear that large viruses (e.g.
Vaccinia) and
Listeria monocytogenes, share common strategies
in invasion and intercellular spread.
Included in series
Advances in Cellular and Molecular Biology of Membranes and Organelles
