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CLINICAL HEMATOLOGY
Clinical Hematology
Text with CD-ROM
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By
Neal Young, MD, Bethesda, MD
Stanton Gerson, MD, Shiverick Professor of Hematological Oncology; Director, Case Comprehensive Cancer Center; Director, Ireland Cancer Center; Director, Center for Stem Cell and Regenerative Medicine, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA
Katherine High, MD, William H. Bennett Professor of Pediatrics, University of Pennsylvania School of Medicine; Investigator, Howard Hughes Medical Institute; Director, Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA, USA

Description
Written by a young, innovative author group, this exciting new book gives you the clinically relevant aspects of hematology in an innovative, unique format. The book is structured to comprehensively cover the complete scope of hematology, but allows fast access to key information you need in everyday practice. A section on consultative hematology includes chapters on special populations (pregnancy, pediatrics, geriatrics), infections of marrow and blood, and hematologic problems of medical practice and surgery. You'll also find a section on tools for the hematologist, covering clinical aspects of transfusion, transplantation, and the latest innovative laboratory procedures.

Contents
I. Basic Science of Hematology

* Hematopoiesis (including cytokines)
* Globin/Heme
* Erythrocyte structure
* Red cell antigens
* Granulocyte biology
* Lymphocyte biology (including Ig)
* Megakaryocytes and platelets
* Coagulation factors
* Vascular biology

II. Hematologic Diseases

Section 1. Diseases of Hematopoietic Cell Production

* Marrow failure
* Acquired aplastic anemia
* Fanconi anemia and dyskeratosis congenital
* Pure red cell aplasia
* Myelodysplastic syndromes
* Hairy cell leukemia
* Large granular lymphocytic leukemia
* Mineral and vitamin deficiencies
* Iron deficiency
* Pernicious anemia and folate deficiency
* Anemia of chronic disease

Section 2. Diseases of blood cell destruction

* Hemolytic anemias
* Inherited HA
* Sickle cell disease and other hemoglobinopathies
* Thalassemias
* Hereditary spherocytosis
* RBC enzymopathies
* Acquired HA
* Autoimmune HA
* Paroxysmal nocturnal hemoglobinuria
* Mechanical HA
* Immune thrombocytopenias
* ITP, PTP, neonatal TP
* Drug-induced thrombocytopenia
* Heparin-induced thrombocytopenia
* TTP and HUS
* Neutropenias
* Kostmann's and other onstitutional neutropenias
* Agranulocytosis, pure white cell aplasia

Section 3. Malignant and proliferative hematologic diseases

* Leukemias
* Leukemias: diagnosis and classifications
* Acute myelogenous leukemia
* Secondary MDS/AML
* Chronic myelogenous and myelomonocytic leukemia
* Acute lymphocytic leukemia
* Pediatric leukemias
* Chronic lymphocytic leukemia
* Myeloproliferative diseases
* Polycythemia vera and essential thrombocytosis
* Myelofibrosis
* Hypereosinophilia
* Lymphomas and lymphoid malignancies
* Biology of lymphoid malignancy
* Hodgkins disease
* Cutaneous lymphomas
* CNS lymphomas
* NonHodgkins lymphomas
* Infectious malignancies
* HIV-1 and HTLV-1-associated lymphomas
* EBV, HHV-8
* Cryoglobulinemia
* Multiple myeloma
* MGUS
* Macroglobulinemia
* Histiocytosis
* Amyloidosis
* Mastocytosis
* Diseases of the spleen

Section 4. Inherited and Acquired Metabolic Blood Diseases

* Porphyrias
* Hemochromatosis
* Familial Mediterranean fever
* ALPS

Section 5. Diseases of Altered Coagulation
Bleeding Disorders

* Platelet diseases
* Inherited and acquired platelet disorders
* von Willebrands disease
* Coagulation factor disorders
* Hemophilias (F VIII and IX deficiencies)
* Acquired inhibitors
* Thrombotic disorders
* Inherited deficiencies of proteins C, S; factor V * Leiden
* Anti-phospholipid syndrome
* Heparin-induced thrombocytopenia

III. Consultative Hematology

Section 1. Hematology of Growth, Development, and Aging

* Hematologic complications of pregnancy
* Hematology of the newborn
* Pediatric hematology
* Geriatric hematology

Section 2. Infections of Marrow and Blood
Viruses

* Epstein-Barr virus
* CMV
* HHV-8 and other herpesviruses
* Parvovirus B19
* HIV-1 and the hematology of AIDS
* Hepatitis C
* Dengue and hemorrhagic fever viruses
* Protozoa
* Malaria
* Bartonellosis and others
* Parasites
* Hookworm

Section 3. Hematologic Problems of Medical Practice
Anemia

* Hematologic drug reactions
* Erythrocytosis
* Kidney disease
* Liver disease
* Chronic bruising and the bleeding diathesis evaluation
* Venous and arterial thrombosis
* Anticoagulant therapy
* Disseminated intravascular coagulation
* Chemotherapy toxicities and complications

Section 4. Hematologic Complications in Surgery

* Evaluation of the acutely bleeding patient
* Surgery in specific hematologic conditions

IV. Tools for the Hematologist

Section 1. Specialized practice

* HLA and Transplantation of Unrelated Cells
* Marrow and blood transplantation
* Supportive care during transplantation
* Graft-versus-host disease
* Transfusion medicine
* Practice of blood component transfusion
* Complications of transfusion (incl hepatitis, 2o iron overload)

Section 2. Laboratory methods

* Blood and marrow morphology (incl histochemistry)
* Flow cytometry
* Cytogenetics/FISH
* DNA/functional genomics
* Coagulation testing

Bibliographic details
Hardbound, 1456 pages, publication date: DEC-2005
ISBN-13: 978-0-323-01908-8
ISBN-10: 0-323-01908-0
Imprint: MOSBY


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Last update: 10 Sep 2009
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