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| USING EYE MOVEMENTS AS AN EXPERIMENTAL PROBE OF BRAIN FUNCTION, 171
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A Symposium in Honor of Jean Büttner-Ennever
To order this title, and for more information, click here
Edited By
R. Leigh, Department of Neurology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA
Christopher Kennard, Academic Unit of Neuroscience, Charing Cross Hospital, London, UK
Included in series
Progress in Brain Research,
Description
This volume of Progress in Brain Research is based on the proceedings of a conference, "Using Eye Movements as an Experimental
Probe of Brain Function," held at the Charing Cross Hospital Campus of Imperial College London, UK on 5th -6th December, 2007 to honor
Professor Jean Buttner-Ennever. With 87 contributions from international experts – both basic scientists and clinicians – the volume
provides many examples of how eye movements can be used to address a broad range of research questions. Section 1 focuses on extraocular
muscle, highlighting new concepts of proprioceptive control that involve even the cerebral cortex. Section 2 comprises structural, physiological,
pharmacological, and computational aspects of brainstem mechanisms, and illustrates implications for disorders as diverse as opsoclonus,
and congenital scoliosis with gaze palsy. Section 3 addresses how the cerebellum transforms neural signals into motor commands, and how
disease of such mechanisms may lead to ataxia and disorders such as oculopalatal tremor. Section 4 deals with sensory-motor processing
of visual, vestibular, somatosensory, and auditory inputs, such as are required for navigation, and gait. Section 5 illustrates how eye
movements, used in conjunction with single-unit electrophysiology, functional imaging, transcranial magnetic stimulation, and lesion
studies have illuminated cognitive processes, including memory, prediction, and even free will. Section 6 includes 18 papers dealing
with disorders ranging from congenital to acquired forms of nystagmus, genetic and degenerative neurological disorders, and treatments
for nystagmus and motion sickness.
Audience
Neuroscientists, neurologists, opthalmologists, cognitive neuroscientists, and visual sciences.
Contents
Section 1: Using Novel Techniques to Define the Neural Substrate for Eye Movements
Jean Buttner-Ennever, Munich: Re-mapping the oculomotor
system
Joseph Demer, Los Angeles: Using high-definition MRI to re-define the mechanics of eye rotations
Michael Goldberg, New York: The
cortical representation of oculomotor proprioception
David Zee, Baltimore: How new knowledge of the anatomy of the eye muscles and their
innervation translates into improved treatment of patients with ocular motor palsies
Paul Knox, Liverpool: Testing the influences of
extraocular proprioception in humans
James Sharpe, Toronto: Reinterpreting palsies of the ocular motor nerves
Dominik Straumann: New
insights into trochlear nerve palsy
Paul May: Anatomical insights into peripheral gaze control
Louis Dell?Osso: How disrupting ocular
proprioception can be therapy for congenital nsyatgmus
Section 2: New Insights into Brainstem Generation of Ocular Motor Commands
Anja
Horn, Munich: New insights into the circuitry and pharmacology of the brainstem reticular formation
Edward Keller, San Francisco: Using
multiple electrode arrays to map moving fields of neural activity in the superior colliculus
Paul Gamlin, Birmingham: Synthesis of vergence
control by brainstem circuits
Holger Rambold, Lubeck: Disturbances of vergence and saccadic eye movements by human brainstem lesions
Christoph Helmchen, Luebeck: Understanding how the cerebellar disease could cause saccadic oscillations
Stefano Ramat, Pavia: A brainstem
network that accounts for abnormal saccades
Mark Gibson, Belfast: Human saccadic disorders and their brainstem mechanisms
Richard Clement:
A black-box approach to saccadic disorders
Section 3: Using Eye Movements as an Index of Transformation of Signals by the Cerebellum
Stephen Highstein, St. Louis: How the cerebellar transforms sensory inputs into motor commands
Albert Fuchs, Seattle: How visual and
motor signals interact in the cerebellum
John Stahl, Cleveland: How mutant mice with calcium channel defects provide insight into the
cerebellar role in balance
Michael Strupp, Munich: How knowledge about calcium channel disorders translates into treatment of human cerebellar
disease
Bernard Cohen, New York: Cerebellar governance of vestibular mechanisms
Mark Walker, Baltimore: Influence of cerebellar nodulus
on translational vestibulo-ocular reflex
Ulrich Buttner, Munich: Control of smooth-pursuit eye movements by cerebellum
Robert McCrea,
Chicago: Influence of cerebellum on combined eye-head tracking
Adolfo Bronstein, London: Degenerative disorders that affect the cerebellar
control of eye movements
Section 3: Using Eye Movements as a Probe of Sensory-Motor Processing
Frederick Miles, Bethesda: How the brain
uses visual motion as we move through the environment
Peter Hoffmann: How motion signals are encoded in visual areas
Michael Mustari,
Atlanta: How disturbed maturation of visual motion processing leads to nystagmus in infancy
Thomas Brandt: How vestibular and visual
inputs may be abnormally processed in cerebral cortex
Richard Abadi, Manchester: Visual perceptions during ocular oscillations
Michael
Gresty, London: Self-motion, gaze control and visual perception
Bernhard Hess, Zurich: Understanding interactions between responses
to head rotations and translations
Michael Halmagyi, Sydney: Probing otolith-ocular reflexes using novel stimuli in humans
Sergei Yakushin,
New York: How visual inputs from subcortical pathways influence perception of self-motion
Section 4: Using Eye Movements as a Probe
of Cognition
James Lynch, Jackson: Concepts of the contribution of cerebral cortex based on new anatomical findings
Kikuro Fukushima,
Sapporo: Prediction, eye movements, and the frontal lobes
Rene Muri, Bern: Using transcranial magnetic stimulation to probe decision-making
and memory
Parashkev Nachev, London: Using functional imaging to during conflict resolution and free choice
Charles Pierrot-Deseilligny,
Paris: Using saccades to probe different forms of memory
Christopher Kennard, London: Role of the supplementary eye fields in countermanding
saccades
Masud Husain, London: Using eye movements to probe shifts of instruction set
Graham Barnes, Manchester: Using smooth tracking
movements to probe prediction
R. John Leigh, Cleveland, Ohio: Eye movements: The meaning of it all (Epilogue)
| Bibliographic details |
Hardbound, 652 pages, publication date: SEP-2008
ISBN-13: 978-0-444-53163-6
ISBN-10: 0-444-53163-7
Imprint: ELSEVIER
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