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An Introduction
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By
Robert Crichton, Unit de Biochimie, Universit Catholique de Louvain, Louvain-la-Neuve, Belgium
Description
The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The
study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology
constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience
in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory
chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader
for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt
with next. Thereafter, indivbidual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel
and cobalt, manganese, and finlly molybdenum, vanadium, tungsten and chromium. The final three chapers provide a tantalising view of
the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.
Audience
Student: Chemists / biologists following courses in Inorganic biochemistry / Bioinorganic chemistry. Chemistry, biology, medicine, environmental
sciences
Researcher: Because it is clearly written and gives a homogeneous view of the subject Chemistry, biology, microbiology, plant
science, medical research (preclinical and clinical) environmental research
Consultant: To have access to important informations collected
in one volume. Pharmacological industry, foodstuffs and agro-industries, environmental applications
Contents
The role of metals in biology – an overview
Basic coordination chemistry for biologists
Structural and molecular biology for chemists
Biological ligands for metal ions
An overview of intermediary metabolism and bioenergetics
Methods which can be used to study metals
in biology
Metal assimilation pathways
Transport, storage and homeostasis of metal ions
Sodium and potassium
Calcium
Magnesium
Zinc
Iron
Copper
Nickel and cobalt
Manganese
Molybdenum, vanadium, tungsten and chromium
Metals in brain function
Biomineralisation
Metals
in medicine and the environment
Concluding remarks
| Bibliographic details |
Paperback, 382 pages, publication date: DEC-2007
ISBN-13: 978-0-444-52740-0
ISBN-10: 0-444-52740-0
Imprint: ELSEVIER
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| Price and Ordering |
Price:
USD 99.95
EUR 76.95
GBP 65
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Last update: 25 Nov 2009
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